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Merck
CN

418943

2,2′-[4-(2-Hydroxyethylamino)-3-nitrophenylimino]diethanol

98%

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About This Item

Linear Formula:
HOCH2CH2NHC6H3(NO2)N(CH2CH2OH)2
CAS Number:
Molecular Weight:
285.30
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
251-410-3
MDL number:
Assay:
98%
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InChI key

MIWUTEVJIISHCP-UHFFFAOYSA-N

InChI

1S/C12H19N3O5/c16-6-3-13-11-2-1-10(9-12(11)15(19)20)14(4-7-17)5-8-18/h1-2,9,13,16-18H,3-8H2

SMILES string

OCCNc1ccc(cc1[N+]([O-])=O)N(CCO)CCO

assay

98%

mp

108-111 °C (lit.)

solubility

water: soluble(lit.)

Application

2,2′-[4-(2-Hydroxyethylamino)-3-nitrophenylimino]diethanol may be employed to improve the visibility of self-healing ureidopyrimidinone (UPy) hydrogel (poly(ethylene glycol) containing bifunctional UDP groups).

General description

2,2′-[4-(2-Hydroxyethylamino)-3-nitrophenylimino]diethanol (HC Blue No.2) is a water-soluble purple dye.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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F W Kari et al.
Cell biology and toxicology, 6(2), 139-155 (1990-04-01)
Previous studies indicated that HC Blue 1 induced heptocellular carcinomas in B6C3F1 mice whereas the structurally similar nitroaromatic amine HC Blue 2 did not. In an attempt to elucidate the biochemical mechanisms responsible for their different carcinogenic potencies, comparative metabolism
L E Hill et al.
Mutation research, 241(2), 145-150 (1990-06-01)
2 hair dyes, HC Blue No. 1 and HC Blue No. 2, were evaluated for the in vitro induction of unscheduled DNA synthesis (UDS) in primary hepatocytes of rat, mouse, hamster, rabbit and monkey. NC Blue No. 1, which is
T J Oberly et al.
Mutation research, 241(2), 151-159 (1990-06-01)
The hair-dye ingredients, HC Blue No. 1 (HCB1) and HC Blue No. 2 (HCB2), were tested for the induction of bacterial mutation using Salmonella typhimurium strains TA1535, TA1537, TA98 and TA100; and Escherichia coli strains WP2uvrA-. In addition, both dyes
HC Blue No. 2.
IARC monographs on the evaluation of carcinogenic risks to humans, 57, 143-151 (1993-01-01)
Species comparisons regarding comparative metabolism of two structurally similar phenylenediamines (HC Blue 1 and HC Blue 2).
F Kari et al.
Progress in clinical and biological research, 340D, 305-314 (1990-01-01)

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