421960
Bis(hexamethylene)triamine
high purity
Synonym(s):
6,6′-Iminodihexylamine, Bis(6-aminohexyl)amine
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
Linear Formula:
NH2(CH2)6NH(CH2)6NH2
CAS Number:
Molecular Weight:
215.38
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
205-593-1
Beilstein/REAXYS Number:
2323517
MDL number:
vapor pressure
<0.01 mmHg ( 25 °C)
form
solid
refractive index
n20/D 1.49 (lit.)
bp
163-165 °C/4 mmHg (lit.)
mp
33-36 °C (lit.)
density
0.85 g/mL at 20 °C (lit.), 0.879 g/mL at 25 °C
SMILES string
NCCCCCCNCCCCCCN
InChI
1S/C12H29N3/c13-9-5-1-3-7-11-15-12-8-4-2-6-10-14/h15H,1-14H2
InChI key
MRNZSTMRDWRNNR-UHFFFAOYSA-N
General description
Bis(hexamethylene)triamine (Bis-HEA, BHMT, BHMTA) is an aliphatic polyamine. It is a spermidine analog and has been reported to lack the enhancing effect on mitochondrial Ca(2+) accumulation but shows inhibitory effect on the Ca(2+) and Pi-induced mitochondrial permeability transition. Its ability in inhibiting shale swelling and dispersion in water-based drilling fluid has been investigated.
signalword
Danger
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1A - STOT SE 3
target_organs
Respiratory system
Storage Class
8A - Combustible corrosive hazardous materials
wgk
WGK 1
flash_point_f
235.4 °F - closed cup
flash_point_c
113 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Interior synthesizing of ZnO nanoflakes inside nylon-6 electrospun nanofibers.
Panthi G, et al.
Journal of Applied Polymer Science, 127(3), 2025-2032 (2013)
I Rustenbeck et al.
Biochemistry and molecular biology international, 38(5), 1003-1011 (1996-04-01)
The aliphatic polyamine bis(hexamethylene)triamine, a spermidine analogue, was found to lack the enhancing effect on mitochondrial Ca(2+) accumulation which is typical for the natural polyamines, spermidine and spermine. However, like spermine and spermidine, this compound had a significant inhibitory effect
P A Marks et al.
Proceedings of the National Academy of Sciences of the United States of America, 86(16), 6358-6362 (1989-08-01)
N,N'-Hexamethylenebisacetamide (HMBA) induces transformed cells to differentiate, accompanied by suppression of oncogenicity. Clinical trials have shown that HMBA can cause positive therapeutic responses in some cancer patients, but clinical efficacy may be limited, in part, by dose-related toxicity. Potential improvements