422665
4,5-Dichlorophthalimide
97%
Sign In to View Organizational & Contract Pricing.
Select a Size
About This Item
Empirical Formula (Hill Notation):
C8H3Cl2NO2
CAS Number:
Molecular Weight:
216.02
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Assay:
97%
InChI
1S/C8H3Cl2NO2/c9-5-1-3-4(2-6(5)10)8(13)11-7(3)12/h1-2H,(H,11,12,13)
SMILES string
Clc1cc2C(=O)NC(=O)c2cc1Cl
InChI key
QJPBDGMPYPSJSF-UHFFFAOYSA-N
assay
97%
mp
217-219 °C (lit.)
functional group
chloro
General description
4,5-Dichlorophthalimide (5,6-dichloro-1H-isoindole-1,3(2H)-dione) is a phthalimide derivative. It has been synthesized from 5,6-dichloro-1,3-isobenzofurandione and characterized by 1H ,13C-NMR and IR. The dipole moment, polarizability and first-order hyperpolarizability of 4,5-dichlorophthalimide have been investigated using ab initio and density functional theory calculations.
Application
4,5-Dichlorophthalimide (5,6-dichloro-1H-isoindole-1,3(2H)-dione) is suitable as a reactant in the synthesis of 5′-N-(4′′,5′′-dichlorophthaloyl)-3′-azido-2′,3′-dideoxythymidine and 2-amino-4,5-dichlorobenzoic acid.
It may be used in the following studies:
It may be used in the following studies:
- As a reactant in the synthesis of 4,5-dichloro-1,2-benzenedicarboxamide.
- As an additive in the Ir-BICP catalyzed asymmetric hydrogenation of 2,3,3-trimethylindolenine to improve enantioselectivity.
- As a reactant in the synthesis of octachloro-Cu-phthalocyanine.
- As a reagent in the synthesis of 7-tert-butylthianthrene-2,3-dicarboxylic imide.
- As a starting material in the synthesis of N-(3-bromopropyl)-4,5-dichlorophthalimide.
- As a nucleophilic partner in the phosphine-catalyzed allylic substitution of Morita-Baylis-Hillman acetates to form N-protected β-amino phosphonic acid esters.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Elizabeth Sharlow et al.
Probe Reports from the NIH Molecular Libraries Program, 2010 Dec 15 (Updated 2011 24) (2011-10-01)
The unicellular eukaryote
Jan Balzarini et al.
Antiviral chemistry & chemotherapy, 14(3), 139-144 (2003-10-03)
A variety of substituted 5'-N-phthaloyl-3'-azido-2',3'-dideoxythymidine derivatives has been evaluated for their activity against HIV-1, HIV-2 and Moloney murine sarcoma virus (MSV) in cell culture. Most of the 3'-azido-2',3'-dideoxythymidine (AZT, zidovudine) derivatives showed antiviral activity in the lower micromolar concentration range
I-Line Sensitive Photoacid Generators Having Thianthrene Skeleton.
Okamura H, et al.
J. Photopolym. Sci. Technol., 17(1), 131-134 (2004)
Additive effects in Ir-BICP catalyzed asymmetric hydrogenation of imines.
Zhu G and Zhang X.
Tetrahedron Asymmetry, 9(14), 2415-2418 (1998)
Conversion of phthalimides to isoindolines by diborane.
8 Strassert CA and Awruch J.
Monatshefte fur Chemie / Chemical Monthly, 137(12), 1499-1503 (2006)
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service