422886
(S)-(+)-2-(Aminomethyl)pyrrolidine
97%
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
Empirical Formula (Hill Notation):
C5H12N2
CAS Number:
Molecular Weight:
100.16
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352005
MDL number:
Assay:
97%
Form:
liquid
Quality Level
assay
97%
form
liquid
optical activity
[α]20/D +20°, c = 1 in chloroform
refractive index
n20/D 1.482 (lit.)
bp
65 °C/11 mmHg (lit.)
density
0.933 g/mL at 25 °C (lit.)
functional group
amine
SMILES string
NC[C@@H]1CCCN1
InChI
1S/C5H12N2/c6-4-5-2-1-3-7-5/h5,7H,1-4,6H2/t5-/m0/s1
InChI key
AUKXFNABVHIUAC-YFKPBYRVSA-N
General description
(S)-(+)-2-(Aminomethyl)pyrrolidine is a chiral vicinal diamine.
Application
(S)-(+)-2-(Aminomethyl)pyrrolidine can be used as an organocatalyst:
It can also be used as a reactant to prepare Schiff base metal complexes with pyrrolidine fragment as a ligand in asymmetric synthesis.
- For the asymmetric transformation of (S)-alanine.
- In the asymmetric α-fluorination of linear and branched aldehydes using N-fluorobenzenesulfonamide as the fluorinating agent.
It can also be used as a reactant to prepare Schiff base metal complexes with pyrrolidine fragment as a ligand in asymmetric synthesis.
Used in the synthesis of compounds with antitumor activity.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
3 - Flammable liquids
wgk
WGK 3
flash_point_f
116.6 °F - closed cup
flash_point_c
47 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Regulatory Information
危险化学品
This item has
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Articles
Chiral vicinal diamines are of tremendous interest to the synthetic chemist as they are found in many chiral catalysts and pharmaceuticals.
K Morikawa et al.
Journal of pharmaceutical sciences, 80(9), 837-842 (1991-09-01)
The optical isomers of 2-aminomethylpyrrolidine(1,1-cyclobutane- dicarboxylato)platinum(II) (DWA2114, 1), which has potent antitumor activity against various tumors, were synthesized. They were examined for antitumor activity against Colon 26 carcinoma in a sc-iv system, and changes in urinary protein and sugar levels
Dioxovanadium (V) complexes of Schiff bases derived from S-(+)-2-(aminomethyl) pyrrolidine and aromatic o-hydroxycarbonyl compounds: Synthesis, characterization and structure
Kwiatkowski E, et al.
Polyhedron, 25(15), 2809-2814 (2006)
Direct asymmetric α-fluorination of aldehydes
Steiner DD, et al.
Angewandte Chemie (International ed. in English), 44(24), 3706-3710 (2005)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 422886-250MG | 04061832985862 |
| 422886-100MG | 04061835973644 |
| 422886-500MG | 04061837893964 |