42995
trans-1,3-Diphenyl-2,3-epoxypropan-1-one
≥98.0%
Synonym(s):
trans-2-Benzoyl-3-phenyloxirane, trans-Benzalacetophenone oxide
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About This Item
Empirical Formula (Hill Notation):
C15H12O2
CAS Number:
Molecular Weight:
224.25
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
84132
Assay:
≥98.0%
Form:
solid
assay
≥98.0%
form
solid
mp
86-89 °C (lit.)
functional group
ether, ketone, phenyl
SMILES string
O=C([C@H]1O[C@@H]1c2ccccc2)c3ccccc3
InChI
1S/C15H12O2/c16-13(11-7-3-1-4-8-11)15-14(17-15)12-9-5-2-6-10-12/h1-10,14-15H/t14-,15-/m1/s1
InChI key
UQGMJZQVDNZRKT-HUUCEWRRSA-N
General description
trans-1,3-Diphenyl-2,3-epoxypropan-1-one has been reported to efficiently participate in gas-phase Meerwein reaction under both electrospray ionization (ESI) and atmospheric pressure chemical ionization (APCI) conditions. Therapeutic potential of trans-1,3-diphenyl-2,3-epoxypropane-1-one (DPEP), and its anti-inflammatory effects have been studied.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Giulia Licini et al.
Biopolymers, 84(1), 97-104 (2005-08-27)
C(alpha)-tetrasubstituted alpha-amino acids constitute a powerful tool for controlling the conformation of short peptide sequences. Chiral peptides may be used in stereoselective reactions both for asymmetric induction and in kinetic resolution. By reviewing recent data from our own laboratories and
E C Dietze et al.
Biochemical pharmacology, 42(6), 1163-1175 (1991-08-22)
The inhibition of murine cytosolic epoxide hydrolase has been studied with both racemic and enantiomerically pure trans-3-phenylglycidols. These compounds are the first enantioselective, slow binding inhibitors of cytosolic epoxide hydrolase. The (2S,3S)-3-phenylglycidol enantiomer was always a better inhibitor than the
J Seidegård et al.
European journal of biochemistry, 112(3), 643-648 (1980-12-01)
Benzil was found to be a very potent activator of microsomal epoxide hydrolase activity (measured with styrene oxide as substrate) in vitro. The activating effect was uncompetitive and benzil causes approximately ninefold increases in both the apparent V and the
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 42995-25G | 04061832107790 |