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437085

5-O-(tert-Butyldimethylsilyl)-2,3-O-isopropylidene-D-ribonic acid γ-lactone

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About This Item

Empirical Formula (Hill Notation):
C14H26O5Si
CAS Number:
75467-36-6
Molecular Weight:
302.44
PubChem Substance ID:
24867345
UNSPSC Code:
12352200
Beilstein/REAXYS Number:
4296295
MDL number:
MFCD00216623
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assay

97%

optical activity

[α]20/D −47°, c = 0.8 in chloroform

mp

72-74 °C (lit.)

SMILES string

CC(C)(C)[Si](C)(C)OC[C@H]1OC(=O)[C@@H]2OC(C)(C)O[C@H]12

InChI

1S/C14H26O5Si/c1-13(2,3)20(6,7)16-8-9-10-11(12(15)17-9)19-14(4,5)18-10/h9-11H,8H2,1-7H3/t9-,10-,11-/m1/s1

InChI key

VBPYRQYBEKHPKA-GMTAPVOTSA-N

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
09219JH
06804KE
17628BN
04704PS

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Bo Wang et al.
Molecular cell, 74(4), 742-757 (2019-04-14)
Disturbances in autophagy and stress granule dynamics have been implicated as potential mechanisms underlying inclusion body myopathy (IBM) and related disorders. Yet the roles of core autophagy proteins in IBM and stress granule dynamics remain poorly characterized. Here, we demonstrate