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Sigma-Aldrich

2-Ethylhexyl salicylate

99%

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Synonym(s):
Octisalate, Octyl salicylate
Linear Formula:
(HO)C6H4CO2CH2CH(C2H5)(CH2)3CH3
CAS Number:
Molecular Weight:
250.33
Beilstein:
2730664
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.23

Quality Level

Assay

99%

form

liquid

refractive index

n20/D 1.502 (lit.)

bp

189-190 °C/21 mmHg (lit.)

density

1.014 g/mL at 25 °C (lit.)

SMILES string

CCCCC(CC)COC(=O)c1ccccc1O

InChI

1S/C15H22O3/c1-3-5-8-12(4-2)11-18-15(17)13-9-6-7-10-14(13)16/h6-7,9-10,12,16H,3-5,8,11H2,1-2H3

InChI key

FMRHJJZUHUTGKE-UHFFFAOYSA-N

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This Item
W514500PHR10811477943
Octisalate Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1081

Octisalate

Octisalate United States Pharmacopeia (USP) Reference Standard

USP

1477943

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form

liquid

form

-

form

-

form

-

refractive index

n20/D 1.502 (lit.)

refractive index

n20/D 1.502 (lit.)

refractive index

n20/D 1.502 (lit.)

refractive index

n20/D 1.502 (lit.)

bp

189-190 °C/21 mmHg (lit.)

bp

189-190 °C/21 mmHg (lit.)

bp

189-190 °C/21 mmHg (lit.)

bp

189-190 °C/21 mmHg (lit.)

density

1.014 g/mL at 25 °C (lit.)

density

1.014 g/mL at 25 °C (lit.)

density

1.014 g/mL at 25 °C (lit.)

density

1.014 g/mL at 25 °C (lit.)

General description

2-Ethylhexyl salicylate(EHS) is an organic ultraviolet(UV) absorber that can be used as a photostable ingredient in cosmetic formulations. It shows an absorption spectra in the range of 280-320 nm in the UV region.

Application

EHS is a salicylic ester which can be used as an UV filter in sunscreen based creams.

Pictograms

Environment

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Aquatic Chronic 1

Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point(F)

323.6 °F - closed cup

Flash Point(C)

162 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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A pendant peptide endows a sunscreen with water-resistance.
Ellison AJ and Raines RT
Organic & Biomolecular Chemistry, 16(39), 7139-7142 (2018)
Optical and electron paramagnetic resonance studies of the excited triplet states of UV-B absorbers: 2-ethylhexyl salicylate and homomenthyl salicylate.
Sugiyama K, et al.
Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology, 14(9), 1651-1659 (2015)
Beatriz Albero et al.
Journal of chromatography. A, 1248, 9-17 (2012-06-12)
The determination of organic contaminants in soil is a real challenge due to the large number of these compounds with quite different physico-chemical properties. In the present work, an analytical method was developed for the simultaneous determination in soil of
K A Walters et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 35(12), 1219-1225 (1998-02-04)
The human skin penetration of [14C]octyl salicylate from two representative sunscreen vehicles was determined in vitro. 3H-sucrose was incorporated into all formulations and provided a marker for membrane integrity. When applied as a finite dose in an oil-in-water emulsion vehicle
P Clarys et al.
Journal of dermatological science, 27(2), 77-81 (2001-09-05)
Temperature influences the stratum corneum adsorption of several topically applied compounds. This study was designed to evaluate the influence of the temperature on the stratum corneum adsorption of 3 UV filters. The UV filters were solubilized in two vehicles, an

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