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Merck
CN

438170

Poly(ethylene glycol-ran-propylene glycol) monobutyl ether

average Mn ~1,700

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About This Item

Linear Formula:
CH3(CH2)3(OCH2CH2)x[OCH2CH(CH3)]yOH
CAS Number:
UNSPSC Code:
12162002
PubChem Substance ID:
MDL number:
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InChI

1S/C4H10O.C3H8O2.C2H6O2/c1-2-3-4-5;1-3(5)2-4;3-1-2-4/h5H,2-4H2,1H3;3-5H,2H2,1H3;3-4H,1-2H2

SMILES string

OCCO.CCCCO.CC(O)CO

InChI key

QMNOIORHZMRPLS-UHFFFAOYSA-N

mol wt

average Mn ~1,700

refractive index

n20/D 1.458

viscosity

350 cSt(20 °C)(lit.)

bp

>200 °C (lit.)

transition temp

pour point −34 °C

solubility

H2O: soluble at <40 °C

density

1.051 g/mL at 25 °C

Application

Hydraulic fluids, metal working fluids and lubricants, heat transfer fluids, solder assist fluids, quenchants, lubricants, solvents, plasticizers and foam control agents.

Features and Benefits

Good lubricity under load, noncorrosive to metals. Very low ash content, low pour point, excellent thermal stability.

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

235.4 °F - closed cup

flash_point_c

113 °C - closed cup

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Regulatory Information

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J Araújo et al.
International journal of pharmaceutics, 393(1-2), 167-175 (2010-04-07)
The purpose of this study was to develop a novel nanostructured lipid carrier (NLC) for the intravitreal-targeting delivery of triamcinolone acetonide (TA) by direct ocular instillation. A five-level central composite rotable design was used to study the influence of four
Diego A Chiappetta et al.
Nanomedicine (London, England), 8(2), 223-237 (2012-11-24)
To investigate the intranasal administration of poly(ethylene oxide)-poly(propylene oxide) polymeric micelles loaded with high payloads of the first-line antiretroviral drug efavirenz for targeting to the CNS. The effect of micellar size and composition and drug payload was assessed, employing simple
Supramolecular assembly of cyclodextrin-based nanospheres for gene delivery.
Min-min Fan et al.
Journal of controlled release : official journal of the Controlled Release Society, 152 Suppl 1, e141-e142 (2011-12-27)
Tarek A Ahmed et al.
Pharmaceutical development and technology, 16(5), 497-510 (2010-06-17)
A suitable topical formulation of mefenamic acid was developed in order to eliminate the gastrointestinal disorders associated with its oral administration. Drug coprecipitates prepared with different polymers at various drug-to-polymer ratios improved drug solubility and dissolution compared to pure drug
Yun-Chao Chen et al.
Cell biochemistry and biophysics, 60(3), 267-273 (2011-01-22)
The pluronic block copolymers are able to enhance the ultrasound-induced gene delivery in vitro. In the present study, the effects of pluronics on the efficiency of gene transfer into skeletal muscle in vivo under sonoporation were investigated. Plasmid DNA encoding

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