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Merck
CN

440213

Triethoxy(octyl)silane

97%

Synonym(s):

Octyltriethoxysilane

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About This Item

Linear Formula:
CH3(CH2)7Si(OC2H5)3
CAS Number:
Molecular Weight:
276.49
UNSPSC Code:
12352103
NACRES:
NA.23
PubChem Substance ID:
EC Number:
220-941-2
Beilstein/REAXYS Number:
2325287
MDL number:
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InChI key

MSRJTTSHWYDFIU-UHFFFAOYSA-N

InChI

1S/C14H32O3Si/c1-5-9-10-11-12-13-14-18(15-6-2,16-7-3)17-8-4/h5-14H2,1-4H3

SMILES string

CCCCCCCC[Si](OCC)(OCC)OCC

assay

97%

form

liquid

Quality Level

bp

84-85 °C/0.5 mmHg (lit.)

density

0.88 g/mL at 25 °C (lit.)

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General description

Triethoxy(octyl)silane (OCTEO) is a high-reactivity organosilane coupling agent designed for the molecular-level modification of surface
Its molecular structure features an 8-carbon octyl chain and three hydrolytically sensitive ethoxy groups. This architecture ensures the formation of stable, covalent siloxane bonds with inorganic substrates while providing a low-energy, hydrophobic surface with water contact angles often exceeding 150°.
In the realm of nanoelectronics, it serves as an essential "hydrophobization" agent, reducing non-specific binding and preventing water-induced charge leakage in sensitive micro-electronic components.
Refined to a 97% high-purity specification, this grade is optimized for consistency in research and industrial processes requiring reliable, reproducible surface functionalization for point-of-care (POC) diagnostics and molecular-scale circuitry.

Application

As a high-performance alkoxysilane, OCTEO is used to engineer precise hydrophobic interphases and moisture-resistant layers in advanced diagnostic and electronic systems.
Semiconductor Passivation: Utilized to form dense, moisture-resistant Self-Assembled Monolayers (SAMs) on inorganic substrates like silicon and glass. These layers provide critical insulation and protection for semiconductor devices against environmental degradation.
Gas-Phase Biosensing: Employed in the fabrication of low-cost colorimetric sensor arrays. It stabilizes the porosity of sensor substrates, enabling rapid color changes for the real-time detection of toxic gases.
Biomolecule Immobilization: Used in the production of organically modified silane (Ormosil) nanoparticles. These nanostructures can encapsulate enzymes like horseradish peroxidase (HRP), preserving their activity for high-sensitivity biochemical assays.
Micro-patterning & Adhesion: Acts as an adhesion promoter between organic resins and inorganic micro-electrode arrays. Its ability to modulate surface energy is critical for the reliable performance of printed circuit boards (PCBs) and flexible bio-interfaces.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Skin Irrit. 2

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

212.0 °F - closed cup

flash_point_c

100 °C - closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


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A colorimetric sensor array of porous pigments
Analyst, 134(12), 2453-2457 (2009)
Synthesis of hybrid zeolites using a solvent-free method in the presence of different organosilanes.
Petkowicz I, et al.
Microporous and Mesoporous Materials : The Official Journal of the International Zeolite Association, 241(12), 98-106 (2017)
Robust multifunctional superhydrophobic coatings with enhanced water/oil separation, self-cleaning, anti-corrosion, and anti-biological adhesion.
Cho E, et al.
Chemical Engineering Journal, 314, 347-357 (2017)
Fabrication of Superhydrophobic Al5083 Aluminum Alloy for Marine Applications.
Javad F, et al.
Protection of Metals and Physical Chemistry of Surfaces, 54(5), 899-908 (2018)
Danielle R Scheff et al.
Soft matter, 16(24), 5659-5668 (2020-06-11)
Macromolecules can phase separate to form liquid condensates, which are emerging as critical compartments in fields as diverse as intracellular organization and soft materials design. A myriad of macromolecules, including the protein FUS, form condensates which behave as isotropic liquids.

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