Skip to Content
Merck
CN

443697

Ethyl 3-amino-4,4,4-trifluorocrotonate

96%

Synonym(s):

Ethyl 3-amino-4,4,4-trifluoro-2-butenoate

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Linear Formula:
CF3C(NH2)=CHCO2C2H5
CAS Number:
372-29-2
Molecular Weight:
183.13
UNSPSC Code:
12352100
PubChem Substance ID:
24868069
MDL number:
MFCD00068195
Assay:
96%
Form:
liquid

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

InChI

1S/C6H8F3NO2/c1-2-12-5(11)3-4(10)6(7,8)9/h3H,2,10H2,1H3

SMILES string

CCOC(=O)C=C(N)C(F)(F)F

InChI key

NXVKRKUGIINGHD-UHFFFAOYSA-N

assay

96%

form

liquid

refractive index

n20/D 1.424 (lit.)

bp

83 °C/15 mmHg (lit.)

density

1.245 g/mL at 25 °C (lit.)

General description

Ethyl 3-amino-4,4,4-trifluorocrotonate is an ester.

Application

Ethyl 3-amino-4,4,4-trifluorocrotonate may be employed for the preparation of 4-trifluoromethyl-1,3-oxazin-6-ones and 4-quinolinone derivatives.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Eye Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

149.0 °F - closed cup

flash_point_c

65 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

新产品
This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
MKCF7681
MKCC5366
MKBW5958V
MKBP4448V
MKBK3487V

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

A convenient route to diverse heterocycles through an addition of ?-amino carbonyl compounds to 3-halogeno-4-methoxybenzynes.
Yoon K, et al.
The Journal of Organic Chemistry, 70(14), 5741-5744 (2015)
Journal of Heterocyclic Chemistry, 30, 71-71 (1993)
Journal of Heterocyclic Chemistry, 30, 49-49 (1993)
Aliphatic fluorine-containing amino acids.
Kukhar VP and Soloshonok VA.
Russ. Chem. Rev., 60(8), 850-850 (1991)
Syntheses of New 4-Trifluoromethylated 1, 3-Oxazin-6-Ones from the Enamine of Ethyl Trifluoroacetoacetate.
Decock-Plancquaert M-a, et al.
Bull. Soc. Chim. Belg., 101(4), 313-321 (1992)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service