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447331

N-Vinylformamide

Name: <I>N</I>-Vinylformamide
Brand: ALDRICH

98%

Synonym(s):

N-Ethenylformamide, N-VFA, N-Vinyl-N-formylmethanamine

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About This Item

Linear Formula:

HCONHCH=CH₂

CAS Number:

13162-05-5

Molecular Weight:

71.08

NACRES:

NA.23

PubChem Substance ID:

24868334

UNSPSC Code:

12162002

MDL number:

MFCD00081206

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vapor pressure

~0.1 mmHg ( 25 °C)

Quality Level

100

assay

98%

contains

25-55 ppm 4-Hydroxy-TEMPO as stabilizer

refractive index

n20/D 1.494 (lit.)

bp

210 °C (lit.)

mp

−16 °C (lit.)

density

1.014 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

[H]C(=O)NC=C

InChI

1S/C3H5NO/c1-2-4-3-5/h2-3H,1H2,(H,4,5)

InChI key

ZQXSMRAEXCEDJD-UHFFFAOYSA-N

Related Categories

Biomedical Materials

Monomers

Polymerization Tools

General description

N-Vinylformamide is a vinyl monomer with high reactivity and water solubility. It can be used as a monomer to synthesize specialty polymers with stimuli-responsive behavior. It is biocompatible and suitable for use in drug delivery systems, tissue engineering, and controlled-release applications. It also finds application in the field of batteries, adhesives, coatings, biosensors, and water treatment.

Application

N-Vinylformamide can be used: ·

As a monomer to synthesize poly (N-vinylformamide) (PNVF) based hydrogels that can be used for controlled drug delivery.
To synthesize an aqueous binder for Li₄Ti₅O₁₂(LTO) anodes in lithium-ion batteries. This helps to enhance the stability and specific capacity of the electrodes.
To fabricate biocompatible coating for medical devices.
To fabricate polypropylene membranes for continuous removal of organic micropollutants from water. N-vinylformamide enhances the adsorption affinity of the membrane by inducing multiple hydrophilic and hydrogen bonding sites on the surface.

pictograms

GHS08,GHS05,GHS07

signalword

Danger

hcodes

H302,H315,H318,H335,H351,H360D

pcodes

P202 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P308 + P313

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Repr. 1B - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 1

flash_point_f

215.6 °F

flash_point_c

102 °C

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N-vinylformamide-Building block for novel polymer structures

Pinschmidt Jr RK, et al.

Journal of Macromolecular Science, Part A: Pure and Applied Chemistry, 34(10), 1885-1905 (1997)

Synthesis of Water-Soluble Copolymers of N-vinylpyrrolidone with N-vinyldithiocarbamate as Multidentate Polymeric Chelation Systems and Their Complexes with Indium and Gallium.

Nikolay I Gorshkov et al.

Molecules (Basel, Switzerland), 25(20) (2020-10-18)

Dithiocarbamate (DTC) derivatives of N-vinylpyrrolidone-N-vinylamine (VP-VA) copolymers were synthesized via reaction between the copolymers and carbon disulfide in alkaline medium; molecular masses of the products were 12 and 29 kDa; the VP:VDTC ratios were 94:6 and 83:17 mol.%. Complexation between

Novel cationic polyamidine: Synthesis, characterization, and sludge dewatering performance.

Bo Guo et al.

Journal of environmental sciences (China), 51, 305-314 (2017-01-25)

In this study, a new and facile route was employed for synthesis of polyamidine with abundant cations and attractive five-membered ringlike structural unit. N-vinylformamide and acrylonitrile copolymerized firstly to form intermediates, and the intermediates were processed with hydrochloric acid to

pH-Sensitive Polyampholyte Microgels of Poly(Acrylic Acid-co-Vinylamine) as Injectable Hydrogel for Controlled Drug Release.

Yanmin Chen et al.

Polymers, 11(2) (2019-04-10)

pH-sensitive polyampholyte microgels of poly(acrylic acid-co-vinylamine) (P(AA-co-VAm)) were developed as an injectable hydrogel for controlled drug release. The microgels of P(AA-co-VAm) were prepared via inverse suspension polymerization of acrylic acid and N-vinylformamide followed by hydrolysis of poly(N-vinylformamide) (PNVF) chains of

Preparation and Characterization of Thermoresponsive Poly(N-vinylisobutyramide) Microgels

Hiroaki Yoshida, et al.

Langmuir, 38, 5269-5274 (2022)

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Global Trade Item Number

SKU	GTIN
447331-100ML	04061832286969
447331-500ML	04061832288550

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