453625
Fumaric acid monoethyl ester calcium salt
98%
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About This Item
Linear Formula:
(C2H5O2CCH=CHCO2)2Ca
CAS Number:
Molecular Weight:
326.31
UNSPSC Code:
12352100
PubChem Substance ID:
EC Number:
263-369-9
MDL number:
InChI key
WOONQYHBMBCNDD-SYWGCQIGSA-L
InChI
1S/2C6H8O4.Ca/c2*1-2-10-6(9)4-3-5(7)8;/h2*3-4H,2H2,1H3,(H,7,8);/q;;+2/p-2/b2*4-3+;
SMILES string
CCOC(=O)\C=C\C(=O)O[Ca]OC(=O)\C=C\C(=O)OCC
assay
98%
mp
285 °C (dec.) (lit.)
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 1
ppe
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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M Vandermeeren et al.
Biochemical and biophysical research communications, 234(1), 19-23 (1997-05-08)
Most studies on the antipsoriatic mode of action of dimethylfumarate focused on its antiproliferative effects in keratinocytes. Because inflammatory skin diseases are associated with an upregulation of endothelial cell adhesion molecules and because the presence of inflammatory cells in dermis
P J Altmeyer et al.
Journal of the American Academy of Dermatology, 30(6), 977-981 (1994-06-01)
Psoriasis vulgaris may benefit from treatment with fumaric acid and/or its derivatives; however, because different preparations have been used, results have been contradictory and difficult to interpret. The purpose of this clinical trial was to evaluate the therapeutic value of
Dirk W Grijpma et al.
Biomaterials, 26(16), 2795-2802 (2004-12-18)
Biodegradable polymer networks were prepared from fumaric acid derivatives of oligomeric esters. Photo-crosslinkable macromers were prepared by reacting star-shaped hydroxyl-group terminated lactide, epsilon-caprolactone and trimethylene carbonate based oligomers and fumaric acid monoethyl ester in the presence of N,N-dicyclohexylcarbodiimide and 4-dimethylamino
[Therapy of psoriasis with fumaderm preparation].
A Zesch
Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 46(12), 875-876 (1995-12-01)
J Z Hu et al.
Solid state nuclear magnetic resonance, 6(2), 187-196 (1996-04-01)
We show that the spinning side-bands of protonated and non-protonated carbon atoms can be well separated by means of the standard SCP and LCPD experiments at a relatively slow sample spinning rate or at high magnetic field. These experiments offer
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