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Merck
CN

457620

Polyglycolide

inherent viscosity 1.4dL/g

Synonym(s):

PGA, Poly(glycolic acid)

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About This Item

Linear Formula:
(C2H4O3)n
CAS Number:
26124-68-5
NACRES:
NA.23
PubChem Substance ID:
24869373
UNSPSC Code:
12162002
MDL number:
MFCD00148011

Key Documents

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Product Name

Polyglycolide, inherent viscosity 1.4dL/g

InChI

1S/C2H4O3/c3-1-2(4)5/h3H,1H2,(H,4,5)

SMILES string

OCC(O)=O

InChI key

AEMRFAOFKBGASW-UHFFFAOYSA-N

form

solid

degradation timeframe

6-12 months

inherent viscosity

1.1-1.7 dL/g, 0.1 % (w/v) in hexafluoroisopropanol(25 °C)

transition temp

Tm 220-230 °C

solubility

hexafluoroisopropanol: soluble

density

1.53 g/mL at 25 °C (lit.)

storage temp.

2-8°C

Quality Level

100

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Related Categories

Application

Polyglycolide (PGA) along with polylactide may be used to prepare a biodegradable copolymer to be used as implantations. Fabrication of biopolymer/carbon nanotube composite has been reported using PGA fiber as one of the constituents of the composite. Modified porous PGA scaffolds has been fabricated.
medical device

General description

Biodegradable and biocompatible PGA could be potentially useful for bone regeneration. High molecular weight polyglycolide (PGA) can be prepared by ring opening polymerization of diglycolide in the presence of diphenyl bismuth bromide.
Biodegradable polymer

Preparation Note

To achieve solubility in hexafluoroisopropanol, melt crystalline product and quench with liquid nitrogen to change material to amorphous form.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
MKCV5213
MKCN9577
MKCC4011
MKBQ7102V
MKBJ2002V

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Effect of dsDNA wrapped single-walled carbon nanotubes on the thermal and mechanical properties of polycaprolactone and polyglycolide fiber blend composites
Spearman SS
Polymer, 56(15), 476-481 (2015)
Fast Synthesis of High-Molecular-Weight Polyglycolide Using Diphenyl Bismuth Bromide as Catalyst
Lu Y, et al.
Macromolecular Chemistry and Physics, 216(4), 395-399 (2015)
Preliminary report on the osteogenic potential of a biodegradable copolymer of polyactide (PLA) and polyglycolide (PGA)
Hollinger JO
Journal of Biomedical Materials Research Part A, 17(1) (1983)
Diopside modified porous polyglycolide scaffolds with improved properties
Feng P, et al.
Royal Society of Chemistry Advances, 5, 54822-54829 (2015)
Andrew K Capulli et al.
Biomaterials, 133, 229-241 (2017-04-27)
Tissue engineered scaffolds have emerged as a promising solution for heart valve replacement because of their potential for regeneration. However, traditional heart valve tissue engineering has relied on resource-intensive, cell-based manufacturing, which increases cost and hinders clinical translation. To overcome

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