462128
6-Methylpyridine-2-carboxylic acid
Synonym(s):
2-Carboxy-6-methylpyridine, 6-Methylpicolinic acid, NSC 109143, NSC 26023
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About This Item
Empirical Formula (Hill Notation):
C7H7NO2
CAS Number:
Molecular Weight:
137.14
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
form
solid
bp
100 °C/4.5 mmHg (lit.)
mp
120-127 °C (lit.)
SMILES string
Cc1cccc(n1)C(O)=O
InChI
1S/C7H7NO2/c1-5-3-2-4-6(8-5)7(9)10/h2-4H,1H3,(H,9,10)
InChI key
LTUUGSGSUZRPRV-UHFFFAOYSA-N
General description
6-Methylpyridine-2-carboxylic acid (2-carboxy-6-methylpyridine, 6-methylpicolinic acid) is a heterocyclic building block.
Application
6-Methylpyridine-2-carboxylic acid may be used in the preparation of 2-(2-benzoxazolyl)-6-methylpyridine and 1,5-cyclooctadiene iridium(I) complexes bearing chelating ligands.
Pharmacological activity studied in regard to:
Reactant for:
Biological studies of insulin-enhancing complexes
- Interactions of carrier ligands of antidiabetic metal complexes with human serum albumin
- Ability to chelate metalloenzyme inhibitors
- Interactions of insulin-mimetic zinc(II) complexes with cell constituents
Reactant for:
- Synthesis of inhibitors of human 11β -hydroxysteroid dehydrogenase type 1
- Lewis base organocatalysts for stereoselective hydrosilylation reactions
Biological studies of insulin-enhancing complexes
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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