462128
6-Methylpyridine-2-carboxylic acid
Synonym(s):
2-Carboxy-6-methylpyridine, 6-Methylpicolinic acid, NSC 109143, NSC 26023
Sign Into View Organizational & Contract Pricing
Select a Size
About This Item
Empirical Formula (Hill Notation):
C7H7NO2
CAS Number:
Molecular Weight:
137.14
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
form
solid
bp
100 °C/4.5 mmHg (lit.)
mp
120-127 °C (lit.)
SMILES string
Cc1cccc(n1)C(O)=O
InChI
1S/C7H7NO2/c1-5-3-2-4-6(8-5)7(9)10/h2-4H,1H3,(H,9,10)
InChI key
LTUUGSGSUZRPRV-UHFFFAOYSA-N
General description
6-Methylpyridine-2-carboxylic acid (2-carboxy-6-methylpyridine, 6-methylpicolinic acid) is a heterocyclic building block.
Application
6-Methylpyridine-2-carboxylic acid may be used in the preparation of 2-(2-benzoxazolyl)-6-methylpyridine and 1,5-cyclooctadiene iridium(I) complexes bearing chelating ligands.
Pharmacological activity studied in regard to:
Reactant for:
Biological studies of insulin-enhancing complexes
- Interactions of carrier ligands of antidiabetic metal complexes with human serum albumin
- Ability to chelate metalloenzyme inhibitors
- Interactions of insulin-mimetic zinc(II) complexes with cell constituents
Reactant for:
- Synthesis of inhibitors of human 11β -hydroxysteroid dehydrogenase type 1
- Lewis base organocatalysts for stereoselective hydrosilylation reactions
Biological studies of insulin-enhancing complexes
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
新产品
This item has
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Guo Hai Xu et al.
Acta crystallographica. Section C, Crystal structure communications, 62(Pt 12), m581-m583 (2006-12-07)
The title compound, [CrSn(C6H5)3(C7H6NO2)3Cl][Sn(C6H5)3Cl(CH4O)], was obtained from the reaction of Ph3SnCl with the complex [Cr(C7H6NO2)3] in methanol. The structure contains [Ph3SnCl(MeOH)] (A) and [Ph3SnClCr(C7H6NO2)3] (B) molecules. In molecule A, the Sn atom of Ph3SnCl is coordinated by one methanol molecule.
Rong Gao et al.
Dalton transactions (Cambridge, England : 2003), (41)(41), 5645-5651 (2008-10-16)
A series of new nickel complexes bearing benzoxazolylpyridines was synthesized and characterized by FT-IR spectroscopic and elemental analysis. The molecular structures of two representative complexes were determined by single-crystal X-ray diffraction. The complex [NiCl2[2-(2-benzoxazolyl)-6-methylpyridine]] (5) is a centrosymmetric dinuclear compound
Catalytic dehydrogenation of cyclooctane with neutral iridium (I) complexes.
Taubmann S and Alt HG.
Journal of Organometallic Chemistry, 693(10), 1808-1814 (2008)
Ken-Ichi Ohno et al.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 34(9), 1017-1021 (2018-08-07)
In this study, proton affinitive derivatization using picolinic acid and its analogs (3- and 6-methylpicolinic acid and 5-butylpicolinic acid) with proton affinitive moieties was performed for the highly sensitive determination of testosterone (T) and 5α-dihydrotestosterone (DHT) in saliva by LC-ESI-MS/MS.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service