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Merck
CN

462128

6-Methylpyridine-2-carboxylic acid

Synonym(s):

2-Carboxy-6-methylpyridine, 6-Methylpicolinic acid, NSC 109143, NSC 26023

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About This Item

Empirical Formula (Hill Notation):
C7H7NO2
CAS Number:
Molecular Weight:
137.14
UNSPSC Code:
12352100
PubChem Substance ID:
EC Number:
213-287-4
MDL number:
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form

solid

bp

100 °C/4.5 mmHg (lit.)

mp

120-127 °C (lit.)

SMILES string

Cc1cccc(n1)C(O)=O

InChI

1S/C7H7NO2/c1-5-3-2-4-6(8-5)7(9)10/h2-4H,1H3,(H,9,10)

InChI key

LTUUGSGSUZRPRV-UHFFFAOYSA-N

General description

6-Methylpyridine-2-carboxylic acid (2-carboxy-6-methylpyridine, 6-methylpicolinic acid) is a heterocyclic building block.

Application

6-Methylpyridine-2-carboxylic acid may be used in the preparation of 2-(2-benzoxazolyl)-6-methylpyridine and 1,5-cyclooctadiene iridium(I) complexes bearing chelating ligands.
Pharmacological activity studied in regard to:
  • Interactions of carrier ligands of antidiabetic metal complexes with human serum albumin
  • Ability to chelate metalloenzyme inhibitors
  • Interactions of insulin-mimetic zinc(II) complexes with cell constituents

Reactant for:
  • Synthesis of inhibitors of human 11β -hydroxysteroid dehydrogenase type 1
  • Lewis base organocatalysts for stereoselective hydrosilylation reactions

Biological studies of insulin-enhancing complexes


pictograms

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signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves



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