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About This Item
Linear Formula:
ClC6H3(OCH3)CONHCH2C6H4SO2NH2
CAS Number:
Molecular Weight:
368.84
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Quality Level
Assay
95%
mp
209-214 °C (lit.)
functional group
amide
chloro
SMILES string
COc1ccc(Cl)cc1C(=O)NCCc2ccc(cc2)S(N)(=O)=O
InChI
1S/C16H17ClN2O4S/c1-23-15-7-4-12(17)10-14(15)16(20)19-9-8-11-2-5-13(6-3-11)24(18,21)22/h2-7,10H,8-9H2,1H3,(H,19,20)(H2,18,21,22)
InChI key
KVWWTCSJLGHLRM-UHFFFAOYSA-N
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General description
5-Chloro-2-methoxy-N-[2-(4-sulfamoylphenyl)ethyl]benzamide is an organic building block. It has been reported as an intermediate in the synthesis of glyburide. Synthesis of 5-chloro-2-methoxy-N-[2-(4-sulfamoylphenyl)ethyl]benzamide has been reported.
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Molecular regulation of cell fate in cerebral ischemia: role of the inflammasome and connected pathways
Trendelenburg G.
Journal of Cerebral Blood Flow and Metabolism (2014)
Reply to Letter Regarding Article," NLRP3 Inflammasome as a Therapeutic Target in Myocardial Infarction.
Takahashi M.
International Heart Journal, 55(4), 380-380 (2014)
Carlo Marchetti et al.
Journal of cardiovascular pharmacology, 63(4), 316-322 (2013-12-18)
The formation of the NLRP3 inflammasome in the heart during acute myocardial infarction amplifies the inflammatory response and mediates further damage. Glyburide has NLRP3 inhibitory activity in vitro but requires very high doses in vivo, associated with hypoglycemia. The aim
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