466387
Brij® S 100
average Mn ~4,670
Synonym(s):
Polyoxyethylene (100) stearyl ether
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About This Item
Linear Formula:
C18H37(OCH2CH2)nOH, n~100
CAS Number:
MDL number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23
mol wt
average Mn ~4,670
Quality Level
mp
51-54 °C (lit.)
hydroxyl value
13‑25 mg KOH/g
solubility
propylene glycol and xylene: insoluble
density
1.1 g/mL at 25 °C (lit.)
HLB
18
SMILES string
O(CC[O])CCCCCCCCCCCCCCCCCC
InChI
1S/C20H41O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-19-22-20-18-21/h2-20H2,1H3
InChI key
PSEGVHKUPXNGGJ-UHFFFAOYSA-N
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Application
Brij® S 100 may be used:
- as a non-ionic surfactant to study its interactions with luminol electrochemiluminescence for bioanalysis
- as a carrier material to study the formulation of nimodipine, fenofibrate, and o-vanillin using the particles from gas-saturated solution (PGSS) process
- as a hydrophilic surfactant in the casting solution to prepare an asymmetric flat sheet nanofiltration membranes and to study its effects on the hydrophilic property of the poly(ethersulfone) (PES) nanofiltration membranes
Legal Information
Brij is a registered trademark of Croda International PLC
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Formulation of nimodipine, fenofibrate, and o-vanillin with Brij S100 and PEG 4000 using the PGSS process
Kravanja G, et al.
Journal of Supercritical Fluids, 135, 245-253 (2018)
Lingyan Song et al.
Journal of colloid and interface science, 328(2), 374-384 (2008-10-17)
Patternable nanoporous silica thin films with pore sizes on multiple length scales are fabricated using preformed block copolymer/homopolymer blend films as templates. Previous work by Tirumala et al. [V.R. Tirumala, R.A. Pai, S. Agarwal, J.J. Testa, G. Bhatnagar, A.H. Romang
S X Liu et al.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 11(3), 279-282 (1995-01-01)
Although sufficient amount of glucagon can be taken up into systemic circulation through ocular route, the concentration of eyedrops needed at 7.5% would be too high and the price of the doses would be too expensive to be desirable. Attempts
Joanna M Koziara et al.
Journal of controlled release : official journal of the Controlled Release Society, 99(2), 259-269 (2004-09-24)
Despite the advances in tumor therapy, patients with primary brain tumors and brain metastases have a very poor prognosis. Low responses to chemotherapy are mainly attributed to impermeability of the blood-brain barrier to cytotoxic agents. Paclitaxel has been shown to
Tatsuaki Tagami et al.
Journal of controlled release : official journal of the Controlled Release Society, 152(2), 303-309 (2011-02-23)
We have developed a novel and simplified thermosensitive liposomal formulation (HaT: Hyperthermia-activated cytoToxic) composed of DPPC lipid and Brij78 (96:4, molar ratio). The HaT nanoparticles were loaded with doxorubicin (DOX) with >95% efficiency when a pH gradient method and a
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