474789
(S)-(−)-Glycidol
97%, optical purity ee: 98% (GLC)
Synonym(s):
(S)-(−)-2,3-Epoxy-1-propanol, (S)-(−)-Oxirane-2-methanol
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
Empirical Formula (Hill Notation):
C3H6O2
CAS Number:
Molecular Weight:
74.08
UNSPSC Code:
12352005
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
79783
Assay:
97%
assay
97%
optical activity
[α]20/D −15°, neat
optical purity
ee: 98% (GLC)
refractive index
n20/D 1.433 (lit.)
bp
66-67 °C/19 mmHg (lit.)
density
1.116 g/mL at 20 °C (lit.)
functional group
ether, hydroxyl
storage temp.
−20°C
SMILES string
OC[C@H]1CO1
InChI
1S/C3H6O2/c4-1-3-2-5-3/h3-4H,1-2H2/t3-/m0/s1
InChI key
CTKINSOISVBQLD-VKHMYHEASA-N
General description
Glycidol or 2,3-epoxy-1-propanol is a highly reactive epoxy derivative, which is generally used as a monomer in the preparation of many polymers like polyesters, polycarbonates, polyurethanes, and polyamides. It is also used in the preparation of detergents, rubbers, perfumes, fabric dyes, varnishes, cosmetics, and paints.
Application
Employed in the synthesis of chiral (E)-allylic alcohol side-chains for introduction into prostacyclin and prostaglandin frameworks by cross-metathesis.
signalword
Danger
Hazard Classifications
Acute Tox. 2 Inhalation - Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Carc. 1B - Eye Irrit. 2 - Muta. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
161.6 °F
flash_point_c
72 °C
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
A simplified early stage assessment of process intensification: glycidol as a value-added product from epichlorohydrin industry wastes
Cespi D, et al.
Green Chemistry, 18(16), 4559-4570 (2016)
Neil A Sheddan et al.
Organic letters, 8(14), 3101-3104 (2006-06-30)
[reaction: see text] A cross metathesis (CM) approach has been successfully applied to introduce fully functionalized omega-side chain appendages of various prostacyclin and prostaglandin analogues, resulting in high (E)-selectivities for the C13-C14 double bond and leading to the total syntheses
One-pot synthesis of glycidol from glycerol and dimethyl carbonate over KF/sepiolite catalyst
Algoufi YT, et al.
Applied Catalysis A: General, 487, 181-188 (2014)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 474789-1G | 04061832361444 |
| 474789-5G | 04061832361451 |