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Merck
CN

480959

Glycolamide

98%

Synonym(s):

2-Hydroxyacetamide

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About This Item

Linear Formula:
HOCH2CONH2
CAS Number:
Molecular Weight:
75.07
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Assay:
98%
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InChI

1S/C2H5NO2/c3-2(5)1-4/h4H,1H2,(H2,3,5)

SMILES string

NC(=O)CO

InChI key

TZGPACAKMCUCKX-UHFFFAOYSA-N

assay

98%

mp

118-120 °C (lit.)

functional group

amide, hydroxyl

Quality Level

General description

Glycolamide, an isomer of glycine, can be synthesized by the ammonolysis of ethyl glycolate. The conformational analysis of glycolamide has been reported. Its diffusion coefficient in water and partial molal isothermal compressibility has been determined. Its thermodynamic properties have been investigated. Its osmotic and activity coefficients have been obtained.

Application

Glycolamide may be used in the preparation of phosphoglycolamide.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Prasanta K Mohapatra et al.
Inorganic chemistry, 52(5), 2533-2541 (2013-02-12)
Diglycolamide-functionalized calix[4]arenes (C4DGAs) with varying structural modifications were evaluated for actinide complexation from their extraction behavior toward actinide ions such as UO2(2+), Pu(4+), PuO2(2+), and Am(3+) in the room temperature ionic liquid (RTIL) 1-n-octyl-3-methylimidazolium bis(trifluoromethane)sulfonamide (C8mimNTf2). The formation constants were
A Study of the Diffusion of Glycolamide in Water at 25? with the Gouy Interference Method.
Dunlop PJ and Gosting LJ.
Journal of the American Chemical Society, 75(20), 5073-5075 (1953)
R Ruhela et al.
Talanta, 85(2), 1217-1220 (2011-07-06)
A precise, sensitive and selective method for the spectrophotometric determination of palladium (II) using N,N,N',N'-tetra(2-ethylhexyl) thiodiglycolamide T(2EH)TDGA as an extractant is described. Palladium (II) forms yellow colored complex with T(2EH)TDGA which exhibits an absorption maximum at ∼ 300 nm. The
Alan C Cheng et al.
Scientific reports, 8(1), 7570-7570 (2018-05-17)
Small molecules and antibodies each have advantages and limitations as therapeutics. Here, we present for the first time to our knowledge, the structure-guided design of "chemibodies" as small molecule-antibody hybrids that offer dual recognition of a single target by both
New facile synthesis of phosphoglycolohydroxamic acid and other phosphoglycolic acid derivatives.
Weber P, et al.
Tetrahedron Letters, 44(50), 9047-9049 (2003)

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