511188
Methyl indole-5-carboxylate
99%
Synonym(s):
Indole-5-carboxylic acid, methyl ester
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About This Item
Empirical Formula (Hill Notation):
C10H9NO2
CAS Number:
Molecular Weight:
175.18
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Assay:
99%
Quality Segment
assay
99%
mp
126-128 °C (lit.)
functional group
ester
SMILES string
COC(=O)c1ccc2[nH]ccc2c1
InChI
1S/C10H9NO2/c1-13-10(12)8-2-3-9-7(6-8)4-5-11-9/h2-6,11H,1H3
InChI key
DRYBMFJLYYEOBZ-UHFFFAOYSA-N
General description
Methyl indole-5-carboxylate (Methyl 1H-indole-5-carboxylate), a substituted 1H-indole, can be prepared by the esterification of indole-5-carboxylic acid. Its efficacy as a substrate for indigoid generation has been assessed.
Application
Methyl indole-5-carboxylate may be used as a reactant in the following processes:
- biosynthesis of inhibitors of protein kinases
- metal-free Friedel-Crafts alkylation
- preparation of diphenylsulfonium ylides from Martin′s sulfurane
- cross dehydrogenative coupling reactions
- synthesis of indirubin derivatives
- preparation of aminoindolylacetates
Methyl indole-5-carboxylate may be used in the preparation of:
- methyl indoline-5-carboxylate
- 1H-indole-5-carbohydrazide
- dimethyl 1H-indole-3,5-dicarboxylate
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| 511188-5G | 04061832841731 |
| 511188-1G | 04061832491141 |