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About This Item
CAS Number:
MDL number:
UNSPSC Code:
12352112
NACRES:
NA.22
PubChem Substance ID:
Beilstein/REAXYS Number:
3898548
InChI
1S/C27H42NO2.ClH/c1-26(2,3)22-27(4,5)24-13-15-25(16-14-24)30-20-19-29-18-17-28(6,7)21-23-11-9-8-10-12-23;/h8-16H,17-22H2,1-7H3;1H/q+1;/p-1
SMILES string
[Cl-].CC(C)(C)CC(C)(C)c1ccc(OCCOCC[N+](C)(C)Cc2ccccc2)cc1
InChI key
UREZNYTWGJKWBI-UHFFFAOYSA-M
Quality Level
assay
98.2%
form
liquid
concentration
4 mM in H2O
density
0.998 g/mL at 20 °C
General description
Hyamine® 1622 is a cationic detergent benzethonium chloride. Poly(vinyl chloride) membrane ion-selective electrode for the Hyamine 1622 cation has been proposed. Its sorption on soil surfaces has been investigated. It is widely used in cosmetics and shampoos due to its antimicrobial and cationic surfactant properties.
Application
Hyamine® 1622 solution was used as surfactant to examine its acute toxicity and effect on oxidative stress and cholinesterase (ChE) activity in Dugesia japonica. It may be employed as stopping reagent in the improved Eliman procedure for erythrocyte cholinesterase.
Legal Information
Hyamine is a registered trademark of Lonza Group Ltd.
hcodes
pcodes
Hazard Classifications
Aquatic Chronic 3
Storage Class
12 - Non Combustible Liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves
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P M George et al.
Clinical chemistry, 29(2), 365-368 (1983-02-01)
The procedure of Dietz et al. (Clin. Chem. 19: 1309-1313, 1973) for plasma cholinesterase (EC 3.1.1.7) gives a background absorbance of 1.4 A when extended to erythrocyte cholinesterase (EC 3.1.1.8) measurement, because the peak absorbance of the reaction product, 5-thionitrobenzoate
Poly (vinyl chloride) containing dibenzo-18-crown-6 as an ion-selective membrane for hyamine 1622.
Khalil MM, et al.
Analytical Letters, 19(7-8), 807-824 (1986)
Mei-Hui Li
Chemosphere, 70(10), 1796-1803 (2007-10-02)
Eight widely used surfactants (cetyltrimethylammonium bromide; CTAB, benzethonium chloride; Hyamine 1622, 4-nonylphenol; NP, octylphenol ethoxylate; Triton X-100, dodecylbenzene sulfonate; LAS, lauryl sulfate; SDS, pentadecafluorooctanoic acid; PFOA, and perfluorooctane sulfonate; PFOS) were selected to examine their acute toxicities and effects on
Sorption of anionic surfactants SDS, AOT and cationic surfactant Hyamine 1622 on natural soils.
Atay N, et al.
Water, Air, Soil Pollut., 136(1-4), 55-68 (2002)
Elisabeth Lang et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 28(2), 347-354 (2011-08-26)
Benzethonium, an antimicrobial surfactant widely used as preservative of pharmaceuticals, topical wound care product and oral disinfectant, triggers apoptosis of several cell types. The apoptosis is preceded and possibly triggered by mitochondrial depolarization. Even though lacking mitochondria, erythrocytes may similarly
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