Skip to Content
Merck
CN

516414

Sigma-Aldrich

1-(Phenylsulfonyl)-3-indolecarboxaldehyde

97%

Synonym(s):

1-(Benzenesulfonyl)indole-3-carboxaldehyde, 1-(Phenylsulfonyl)-3-formylindole, NSC 628191

Sign Into View Organizational & Contract Pricing

Select a Size

About This Item

Empirical Formula (Hill Notation):
C15H11NO3S
CAS Number:
80360-20-9
Molecular Weight:
285.32
MDL number:
MFCD02681985
UNSPSC Code:
12352100
PubChem Substance ID:
24873888

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Assay

97%

form

solid

mp

157-161 °C (lit.)

SMILES string

[H]C(=O)c1cn(c2ccccc12)S(=O)(=O)c3ccccc3

InChI

1S/C15H11NO3S/c17-11-12-10-16(15-9-5-4-8-14(12)15)20(18,19)13-6-2-1-3-7-13/h1-11H

InChI key

ZLARITBCJILRBL-UHFFFAOYSA-N

Application

Reactant for:
  • Peterson olefination

Reactant for preparation of:
  • Antifungal agents
  • Potential topoisomerase II inhibitors
  • Anti-inflammatory, analgesic and anticonvulsant agents
  • Bacteriorhodopsin analogs
  • Antitumor agents
  • Antitubercular agents
  • Inhibitors of human dUTPase and UNG2
  • Uracil DNA glycosylase inhibitor
  • Anti-HIV and anti-tumor β-carbolines

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

新产品
This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
04419AC

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Ming-Zhi Zhang et al.
European journal of medicinal chemistry, 53, 283-291 (2012-05-09)
A simple and efficient synthetic protocol for 5-(3-indolyl)-oxazoles has been developed and further used to synthesize a series of novel analogues of natural product pimprinine. All new compounds were identified by (1)H NMR, high resolution mass spectrometry, and the structures
Bo Cheng et al.
Organic letters, 12(16), 3622-3625 (2010-08-14)
A concise synthesis of (+/-)-pseudotabersonine from commercially available 1-(phenylsulfonyl)-3-indolecarboxaldehyde has been accomplished. This synthesis features the convergent assembly of a key intermediate via a stepwise variant of a Mannich-type multicomponent coupling process, a double ring-closing metathesis, and a one-pot deprotection/cyclization

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service