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Merck
CN

525286

Sigma-Aldrich

Sucrose acetate isobutyrate solution

90 wt. % in denatured ethanol

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About This Item

Empirical Formula (Hill Notation):
C40H62O19
CAS Number:
126-13-6
Molecular Weight:
846.91
MDL number:
MFCD00041859
UNSPSC Code:
12352201
PubChem Substance ID:
24874316
NACRES:
NA.22

Key Documents

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vapor pressure

40 mmHg ( 20 °C)

Quality Level

100

concentration

90 wt. % in denatured ethanol

bp

105 °C

density

1.1 g/mL at 25 °C

SMILES string

CC(C)C(=O)OC[C@]1(O[C@H](COC(C)=O)[C@@H](OC(=O)C(C)C)[C@@H]1OC(=O)C(C)C)O[C@H]2O[C@H](COC(C)=O)[C@@H](OC(=O)C(C)C)[C@H](OC(=O)C(C)C)[C@H]2OC(=O)C(C)C

InChI

1S/C40H62O19/c1-18(2)33(43)51-17-40(32(57-38(48)23(11)12)29(54-35(45)20(5)6)27(58-40)16-50-25(14)42)59-39-31(56-37(47)22(9)10)30(55-36(46)21(7)8)28(53-34(44)19(3)4)26(52-39)15-49-24(13)41/h18-23,26-32,39H,15-17H2,1-14H3/t26-,27-,28-,29-,30+,31-,32+,39-,40+/m1/s1

InChI key

ZNEBZIJCDDCNRC-SWTLDUCYSA-N

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Pictograms

Flame
GHS02

Signal Word

Danger

Hazard Statements

H225

Hazard Classifications

Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

60.6 °F - closed cup

Flash Point(C)

15.9 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

危险化学品
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Certificates of Analysis (COA)

Lot/Batch Number
MKBH9407
01416BE
06203DB
03429TU
06118DI

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R C Reynolds et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 36(2), 81-93 (1998-03-31)
Sucrose acetate isobutyrate (SAIB), a mixture of esters of sucrose with a composition approximating the name sucrose diacetate hexaisobutyrate, has been used for over 30 yr in many countries as a 'weighting' or 'density-adjusting' agent in non-alcoholic carbonated and non-carbonated
James Lee et al.
Toxicology and applied pharmacology, 215(1), 64-70 (2006-04-25)
Sucrose acetate isobutyrate (SAIB) is a water insoluble, biodegradable gel used for controlled-release oral and subcutaneous drug delivery. We investigated SAIB compatibility in the rat central nervous system (CNS) by implanting solutions of SAIB in adult and in neonatal brains.
Franklin W Okumu et al.
Biomaterials, 23(22), 4353-4358 (2002-09-11)
The purpose of this study was to evaluate the release of recombinant human growth hormone (rhGH) from a novel non-polymeric sustained release system, SABER. The SABER system consists of sucrose acetate isobutryate, a solvent and a polymeric release modifier. Spray
Yaxin Lu et al.
Journal of pharmaceutical sciences, 96(12), 3252-3262 (2007-08-28)
The objective of this study was to develop sustained-release sucrose acetate isobutyrate (SAIB) in situ formulations of risperidone for parenteral delivery. The formulations contained SAIB, solvent (anhydrous ethanol, ethyl lactate, or N-methyl-2-pyrrolidone), and additives such as polylactic acid (PLA). In
P E Noker et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 24(12), 1287-1293 (1986-12-01)
The disposition of 200 mg/kg of 14C-labelled sucrose octa-isobutyrate (14C-SOIB), a component of sucrose acetate isobutyrate (SAIB), a beverage emulsion stabilizer, was studied in rats, dogs and monkeys. After oral administration of 14C-SOIB to three rats, 3-15% of the dose
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