534528
Rink acid resin
50-100 mesh, extent of labeling: 0.6-0.8 mmol/g loading, 1 % cross-linked with divinylbenzene
Synonym(s):
(4-[(2,4-Dimethoxyphenyl)hydroxymethyl]phenol, polymer-bound, Rink acid-labile (hydroxymethyl)polystyrene
SMILES string
C=Cc1ccccc1.C=Cc2ccc(C=C)cc2.COc3ccc(C(O)c4ccc(OCc5ccc(C=C)cc5)cc4)c(OC)c3
crosslinking
1 % cross-linked with divinylbenzene
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
extent of labeling
0.6-0.8 mmol/g loading
particle size
50-100 mesh
application(s)
peptide synthesis
functional group
alcohol
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Application
- Acid labile resin used in Fmoc-based solid phase peptide synthesis.
- Mild acidic cleavage conditions lead to the release of the peptide acid where fully protected peptides can be released if desired.
- Cleavage of the final protected peptide can be achieved in as little as 10% AcOH in DCM or 1% TFA in DCM.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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