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535893

5-Methyluridine

Name: 5-Methyluridine
Brand: ALDRICH

97%

Synonym(s):

Ribothymidine

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About This Item

Empirical Formula (Hill Notation):

C₁₀H₁₄N₂O₆

CAS Number:

1463-10-1

Molecular Weight:

258.23

NACRES:

NA.22

PubChem Substance ID:

24878114

UNSPSC Code:

41106305

EC Number:

215-973-9

MDL number:

MFCD00006535

Assay:

97%

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Properties

assay

97%

mp

183-184 °C (lit.)

SMILES string

CC1=CN([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)C(=O)NC1=O

InChI

1S/C10H14N2O6/c1-4-2-12(10(17)11-8(4)16)9-7(15)6(14)5(3-13)18-9/h2,5-7,9,13-15H,3H2,1H3,(H,11,16,17)/t5-,6-,7-,9-/m1/s1

InChI key

DWRXFEITVBNRMK-JXOAFFINSA-N

Description

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Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Mutagenesis of the modified bases, m(5)U1939 and psi2504, in Escherichia coli 23S rRNA.

Clive Persaud et al.

Biochemical and biophysical research communications, 392(2), 223-227 (2010-01-14)

Ribosomal RNAs (rRNAs) from all kingdoms contain a variety of post-transcriptional modifications and these are typically clustered in the functional centers of the ribosome. The functions of two bases in the 23S rRNA of Escherichia coli that are post-transcriptionally modified

Origins of the large differences in stability of DNA and RNA helices: C-5 methyl and 2'-hydroxyl effects.

S Wang et al.

Biochemistry, 34(12), 4125-4132 (1995-03-28)

Recent studies have shown that there can be large differences in the stability of double and triple helical nucleic acid complexes, depending on whether RNA or DNA strands are involved. These differences have been attributed to structural differences in the

Synthesis of novel 3'-C-methylene thymidine and 5-methyluridine/cytidine H-phosphonates and phosphonamidites for new backbone modification of oligonucleotides.

H An et al.

The Journal of organic chemistry, 66(8), 2789-2801 (2001-04-17)

Novel 5'-O-DMT- and MMT-protected 3'-C-methylene-modified thymidine, 5-methyluridine, and 5-methylcytidine H-phosphonates 1-7 with O-methyl, fluoro, hydrogen, and O-(2-methoxyethyl) substituents at the 2'-position have been synthesized by a new effective strategy from the corresponding key intermediates 3'-C-iodomethyl nucleosides and intermediate BTSP, prepared

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Global Trade Item Number

SKU	GTIN
535893-100G	04061833548202
535893-25G	04061833398876