Skip to Content
Merck
CN

Key Documents

View All Documentation

538795

2-Trifluoromethyl-2-propanol

96%

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Linear Formula:
CF3C(CH3)2OH
CAS Number:
507-52-8
Molecular Weight:
128.09
NACRES:
NA.22
PubChem Substance ID:
24878360
UNSPSC Code:
12352100
EC Number:
208-075-3
MDL number:
MFCD00014391
Assay:
96%
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Quality Level

100

assay

96%

refractive index

n20/D 1.3335 (lit.)

bp

83 °C (lit.)

density

1.17 g/mL at 25 °C (lit.)

functional group

fluoro, hydroxyl

SMILES string

CC(C)(O)C(F)(F)F

InChI

1S/C4H7F3O/c1-3(2,8)4(5,6)7/h8H,1-2H3

InChI key

OCGWWLDZAFOHGD-UHFFFAOYSA-N

General description

2-Trifluoromethyl-2-propanol is a fluorinated aliphatic alcohol. It can be prepared by reacting methyllithium, trifluoroacetone and trifluorovinyl bromide in ether. This can also be synthesized from the reaction between methylmagnesium bromide and 1,1,1-trifluoroacetone in ether.

Application

2-Trifluoromethyl-2-propanol may be employed as a solvent for the preparation of [18F]fluorothymidine. It may also be used in the synthesis of [2-(trifluoromethyl)-2-propyl nitrate] through nitration in nitric acid/trifluoroacetic anhydride.

pictograms

Flame
GHS02

signalword

Danger

hcodes

H225

pcodes

P210

Hazard Classifications

Flam. Liq. 2

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

59.0 °F - closed cup

flash_point_c

15 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

危险化学品

This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
MKCX0222
MKCT6860
MKCQ9769
MKCN7528
MKCM8012

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

The Preparation and Some Reactions of Trifluorovinyllithium1
Tarrant P, et al.
The Journal of Organic Chemistry, 28.3, 839-843 (1963)
Mechanistic studies on gas-phase negative ion unimolecular decompositions. Alkoxide anions
Tumas W, et al.
Journal of the American Chemical Society, 110.9 , 2714-2722 (1988)
Nonacidic nitration of secondary amines
Bottaro JC, et al.
The Journal of Organic Chemistry, 52.11 , 2292-2294 (1987)
View All Related Papers

Global Trade Item Number

SKUGTIN
538795-5G04061837010125