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542946

(S)-(+)-4-Amino-3-hydroxybutyric acid

Name: (<I>S</I>)-(+)-4-Amino-3-hydroxybutyric acid
Brand: ALDRICH

97%

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About This Item

Empirical Formula (Hill Notation):

C₄H₉NO₃

CAS Number:

7013-05-0

Molecular Weight:

119.12

NACRES:

NA.22

PubChem Substance ID:

24878647

UNSPSC Code:

12352116

MDL number:

MFCD00672884

Assay:

97%

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Properties

Quality Level

100

assay

97%

optical activity

[α]20/D +20.0°, c = 1.7 in H₂O

mp

207-212 °C

functional group

amine, carboxylic acid, hydroxyl

SMILES string

NC[C@@H](O)CC(O)=O

InChI

1S/C4H9NO3/c5-2-3(6)1-4(7)8/h3,6H,1-2,5H2,(H,7,8)/t3-/m0/s1

InChI key

YQGDEPYYFWUPGO-VKHMYHEASA-N

Description

General description

(S)-(+)-4-Amino-3-hydroxybutyric acid [(S)-GABOB] can be prepared starting from ethyl (S)-4-chloro-3-hydroxybutyrate.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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[Resolution of (3RS)-4-amino-3-hydroxybutanoic acid (author's transl)].

S Miyamoto et al.

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 99(6), 642-646 (1979-06-01)

Stimulatory effects of gamma-aminohydroxybutyric acid (GABOB) on growth hormone, prolactin and cortisol release in man.

J Takahara et al.

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 12(1), 31-34 (1980-01-01)

Healthy male volunteers injected subcutaneously with 200 mg L-GABOB showed no significant changes in plasma GH, prolactin and cortisol levels. On the other hand, an intrathecal injection of 300 mg D, L-GABOB to cerebrovascular patients caused significant increases in plasma

Different efficacies of d- and l-gamma-amino-beta-hydroxybutyric acids in GABA receptor and transport test systems.

E Roberts et al.

The Journal of neuroscience : the official journal of the Society for Neuroscience, 1(2), 132-140 (1981-02-01)

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Global Trade Item Number

SKU	GTIN
542946-5G	04061832719375
542946-1G	04061825934259