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544051

L-Homophenylalanine hydrochloride

Name: <SC>L</SC>-Homophenylalanine hydrochloride
Brand: ALDRICH

97%

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About This Item

Linear Formula:

C₆H₅CH₂CH₂CH(NH₂)CO₂H · HCl

CAS Number:

21176-60-3

Molecular Weight:

215.68

NACRES:

NA.22

PubChem Substance ID:

24878289

UNSPSC Code:

12352209

MDL number:

MFCD03427064

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Properties

Quality Level

100

assay

97%

optical activity

[α]20/D +38°, c = 1 in 3 M HCl

reaction suitability

reaction type: solution phase peptide synthesis

mp

262-265 °C (dec.) (lit.)

application(s)

peptide synthesis

SMILES string

Cl.N[C@@H](CCc1ccccc1)C(O)=O

InChI

1S/C10H13NO2.ClH/c11-9(10(12)13)7-6-8-4-2-1-3-5-8;/h1-5,9H,6-7,11H2,(H,12,13);1H/t9-;/m0./s1

InChI key

CHBMONIBOQCTCF-FVGYRXGTSA-N

Description

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number

07628BO

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From lead to preclinical candidate: optimization of beta-homophenylalanine based inhibitors of dipeptidyl peptidase IV.

Sonja Nordhoff et al.

Bioorganic & medicinal chemistry letters, 19(16), 4818-4823 (2009-07-07)

A series of highly potent and selective inhibitors of DPP-4 was optimized for ADMET properties. The effort resulted in the discovery of inhibitor 1g, that exhibits excellent efficacy in an oral glucose tolerance test and an attractive pharmacokinetic profile.

Identification of potent 11mer glucagon-like peptide-1 receptor agonist peptides with novel C-terminal amino acids: Homohomophenylalanine analogs.

Tasir S Haque et al.

Peptides, 31(5), 950-955 (2010-02-09)

We report the identification of potent agonists of the Glucagon-Like Peptide-1 Receptor (GLP-1R). These compounds are short, 11 amino acid peptides containing several unnatural amino acids, including (in particular) analogs of homohomophenylalanine (hhPhe) at the C-terminal position. Typically the functional

The role of meta-topolins on the photosynthetic pigment profiles and foliar structures of micropropagated 'Williams' bananas.

Adeyemi O Aremu et al.

Journal of plant physiology, 169(15), 1530-1541 (2012-08-14)

The effect of five topolins (meta-Topolin=mT; meta-Topolin riboside=mTR; meta-Methoxy topolin=MemT; meta-Methoxy topolin riboside=MemTR and 6-(meta-methoxy)-9-(tetrahydropyran-2-yl)-topolin=MemTTHP) on the photosynthetic pigments and leaf structures of micropropagated 'Williams' bananas was compared with the commonly used benzyladenine (BA). Surface-decontaminated explants were cultured for 70

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Global Trade Item Number

SKU	GTIN
544051-1G	04061826095379