556823
4-(4-Chloro-3-(trifluoromethyl)phenyl)-4-piperidinol
97%
Sign Into View Organizational & Contract Pricing
Select a Size
About This Item
Empirical Formula (Hill Notation):
C12H13ClF3NO
CAS Number:
Molecular Weight:
279.69
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Assay
97%
mp
138-141 °C (lit.)
SMILES string
OC1(CCNCC1)c2ccc(Cl)c(c2)C(F)(F)F
InChI
1S/C12H13ClF3NO/c13-10-2-1-8(7-9(10)12(14,15)16)11(18)3-5-17-6-4-11/h1-2,7,17-18H,3-6H2
InChI key
RALRVIPTUXSBPO-UHFFFAOYSA-N
Application
4-(4-Chloro-3-(trifluoromethyl)phenyl)-4-piperidinol may be used to synthesize piperidinols and penfluridol (a neuroleptic agent).
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
新产品
This item has
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Rhodium catalyzed hydroformylation of 1, 1-bis (p-fluorophenyl) allyl or propargyl alcohol: a key step in the synthesis of Fluspirilen and Penfluridol.
Botteghi C, et al.
Tetrahedron, 57(8), 1631-1637 (2001)
Dianqing Sun et al.
Bioorganic & medicinal chemistry, 17(10), 3588-3594 (2009-04-24)
Direct anti-tuberculosis screening of commercially available compound libraries identified a novel piperidinol with interesting anti-tuberculosis activity and drug like characteristics. To generate a structure activity relationship about this hit a 22 member optimization library was generated using parallel synthesis. Products
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service