561053
Diethyl (2-oxobutyl)phosphonate
96%
Synonym(s):
(2-Oxobutyl)phosphonic acid diethyl ester, Diethyl propanoylmethylphosphonate
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About This Item
Linear Formula:
(C2H5O)2PCH2COCH2CH3
CAS Number:
Molecular Weight:
208.19
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352108
MDL number:
Assay:
96%
Product Name
Diethyl (2-oxobutyl)phosphonate, 96%
InChI
1S/C8H17O4P/c1-4-8(9)7-13(10,11-5-2)12-6-3/h4-7H2,1-3H3
SMILES string
CCOP(=O)(CC(=O)CC)OCC
InChI key
GQBVFZDYDHGZPY-UHFFFAOYSA-N
assay
96%
reaction suitability
reaction type: C-C Bond Formation
refractive index
n20/D 1.4360 (lit.)
density
1.072 g/mL at 25 °C (lit.)
Application
Reactant for synthesis of:
- Oxa(bicyclo)octanone for use in preparing cycloheptane annulated furans
- Anatoxin-a and homoanatoxin via the Wittig reaction
- α-Methylene-β-amino ketones
- 2-Amino-5-phosphono- and 2-amino-4-(phosphonomethyl)thiophenes using the Gewald reaction
- Aliphatic musk odorants
- Oxoalkylphosphonates
Storage Class
12 - Non Combustible Liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves
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Nina V Fuchs et al.
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Many microRNAs (miRNAs) are generated from primary transcripts containing multiple clustered stem-loop structures that are thought to be recognized and cleaved by the Microprocessor complex as independent units. Here, we uncover an unexpected mode of processing of the bicistronic miR-15a-16-1
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Molecular cell, 77(6), 1206-1221 (2020-01-26)
Alternative polyadenylation (APA) contributes to transcriptome complexity by generating mRNA isoforms with varying 3' UTR lengths. APA leading to 3' UTR shortening (3' US) is a common feature of most cancer cells; however, the molecular mechanisms are not understood. Here
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Adipocytes deficient in fatty acid synthase (iAdFASNKO) emit signals that mimic cold exposure to enhance the appearance of thermogenic beige adipocytes in mouse inguinal white adipose tissues (iWATs). Both cold exposure and iAdFASNKO upregulate the sympathetic nerve fiber (SNF) modulator
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