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About This Item
Linear Formula:
C6H4OCOCH3BO2C2(CH3)4
CAS Number:
Molecular Weight:
262.11
UNSPSC Code:
12352103
PubChem Substance ID:
MDL number:
InChI
1S/C14H19BO4/c1-10(16)17-12-8-6-11(7-9-12)15-18-13(2,3)14(4,5)19-15/h6-9H,1-5H3
SMILES string
CC(=O)Oc1ccc(cc1)B2OC(C)(C)C(C)(C)O2
InChI key
KHBAJCWEQNVCSN-UHFFFAOYSA-N
assay
97%
form
solid
mp
67-71 °C (lit.)
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Conor N Gruber et al.
Immunity, 53(3), 672-684 (2020-08-05)
Autoinflammatory disease can result from monogenic errors of immunity. We describe a patient with early-onset multi-organ immune dysregulation resulting from a mosaic, gain-of-function mutation (S703I) in JAK1, encoding a kinase essential for signaling downstream of >25 cytokines. By custom single-cell
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