572616
Benzhydryl chloride, polymer-bound
100-200 mesh, extent of labeling: 1.6-2.2 mmol/g loading, 1 % cross-linked with divinylbenzene
crosslinking
1 % cross-linked with divinylbenzene
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
extent of labeling
1.6-2.2 mmol/g loading
particle size
100-200 mesh
Application
This electrophilic resin is used for the attachment of amines alcohols, sulfamates, thiols and phenols using the Fmoc strategy. This resin is an intermediate between the Merrifield resin and the trityl chloride resin in term of acid lability. The carbocation formed during the cleavage reaction is more stable than Merrifield resin but less stable than the trityl chloride resins. The substituents on the benzhydryl chloride can be chosen in order to obtain a less acid labile resin (2-chloro) or a more acid labile resin (4-Methyl) than the benzhydryl chloride resin.
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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