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Merck
CN

61850

L-Leucine ethyl ester hydrochloride

≥99.0% (AT)

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About This Item

Linear Formula:
(CH3)2CHCH2CH(NH2)COOC2H5 · HCl
CAS Number:
Molecular Weight:
195.69
UNSPSC Code:
12352200
PubChem Substance ID:
eCl@ss:
32160406
EC Number:
220-375-6
Beilstein/REAXYS Number:
3994312
MDL number:
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assay

≥99.0% (AT)

form

solid

optical activity

[α]20/D +18.0±1°, c = 5% in ethanol

mp

134-136 °C

application(s)

peptide synthesis

storage temp.

2-8°C

SMILES string

Cl.CCOC(=O)[C@@H](N)CC(C)C

InChI

1S/C8H17NO2.ClH/c1-4-11-8(10)7(9)5-6(2)3;/h6-7H,4-5,9H2,1-3H3;1H/t7-;/m0./s1

InChI key

NOUDPBCEONUCOV-FJXQXJEOSA-N



Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Jaroslav Mráz et al.
Archives of toxicology, 93(3), 603-613 (2019-01-23)
Ethylene oxide (EO), a genotoxic industrial chemical and sterilant, forms covalent adducts with DNA and also with nucleophilic amino acids in proteins. The adduct with N-terminal valine in globin [N-(2-hydroxyethyl)valine (HEV)] has been used in biomonitoring of cumulative exposures to
Peter J Baker et al.
Macromolecular bioscience, 14(11), 1619-1626 (2014-08-27)
We report the encapsulation of three different proteases in bioinspired silica. Silica particles were formed under mild reaction conditions using cationic amine-rich ethyleneamines as initiators, which resulted in aggregations of nanoscale spheres. Following encapsulation, the proteases were characterized for their
David Schachter et al.
American journal of physiology. Gastrointestinal and liver physiology, 306(11), G938-G946 (2014-04-05)
The leucine-to-glutamate (Leu→Glu) pathway, which metabolizes the carbon atoms of l-leucine to form l-glutamate, was studied by incubation of rat tissue segments with l-[U-(14)C]leucine and estimation of the [(14)C]glutamate formed. Metabolism of the leucine carbon chain occurs in most rat