630764
7,8-Dihydroxycoumarin
90%
Synonym(s):
Daphnetin, Daphnetol, Ruixiangsu
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About This Item
Empirical Formula (Hill Notation):
C9H6O4
CAS Number:
Molecular Weight:
178.14
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
Assay
90%
SMILES string
Oc1ccc2C=CC(=O)Oc2c1O
InChI
1S/C9H6O4/c10-6-3-1-5-2-4-7(11)13-9(5)8(6)12/h1-4,10,12H
InChI key
ATEFPOUAMCWAQS-UHFFFAOYSA-N
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Storage Class Code
13 - Non Combustible Solids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Min-Jing Liao et al.
Fundamental & clinical pharmacology, 27(5), 510-516 (2012-06-22)
Chronic exposure to stress hormones might impair cognitive functions such as learning and memory, which were associated with many mood disorders and neurodegenerative diseases. In this study, we aimed to screen for effective compounds to prevent cognitive deficits induced by
Potential utility of daphnetin as a novel treatment for pemphigus vulgaris.
A Feily et al.
Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia, 145(4), 557-558 (2010-09-09)
Jiaqin Liu et al.
Macromolecular bioscience, 4(5), 520-525 (2004-10-07)
Daphnetin (7,8-dihydroxycoumarin), one of the major bioactive components isolated from Daphne koreane Nakai, has been used in traditional Chinese medicine for the treatment of coagulation disorders. It is also a chelator, an antioxidant and a protein kinase inhibitor. In this
Qin Gao et al.
Journal of ethnopharmacology, 120(2), 259-263 (2008-10-07)
Daphnetin was regarded as the mark compound for quality control of Zushima-Pian, a traditional Chinese medicine tablet for treating rheumatoid arthritis (RA). However, no in vivo study on the therapeutic effects of daphnetin for RA has been reported. The adjuvant
Fang Huang et al.
Biomedical and environmental sciences : BES, 19(5), 367-370 (2006-12-28)
To screen the antimalarial compounds of daphnetin derivatives against Plasmodium falciparum in vitro. Plasmodium faciparum (FCC1) was cultured in vitro by a modified method of Trager and Jensen. Antimalarial compounds were screened by microscopy-based assay and microfluorimetric method. DA79 and
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