631175
Methyl 6-chloropyridine-3-carboxylate
98%
Synonym(s):
Methyl 6-chloronicotinate, Methyl 6-chloro-3-picolinate
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
Empirical Formula (Hill Notation):
C7H6ClNO2
CAS Number:
Molecular Weight:
171.58
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Assay:
98%
Quality Level
assay
98%
mp
86-90 °C (lit.)
functional group
chloro, ester
SMILES string
COC(=O)c1ccc(Cl)nc1
InChI
1S/C7H6ClNO2/c1-11-7(10)5-2-3-6(8)9-4-5/h2-4H,1H3
InChI key
RMEDXVIWDFLGES-UHFFFAOYSA-N
Application
Methyl 6-chloropyridine-3-carboxylate can be used to synthesize fluoro substituted 6-phenylnicotinamide, which shows TRPV1 antagonist potency. It can also be used in the synthesis of retinoid x receptor (RXR) ligands, which have many clinical applications.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Sens. 1
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Regulatory Information
新产品
This item has
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
"Replacing alkyl sulfonamide with aromatic sulfonamide in sulfonamide-type RXR agonists favors switch towards antagonist activity"
Morishita I-K, et al.
Bioorganic & Medicinal Chemistry, 19(03), 1001-1003 (2009)
"Design and synthesis of 6-phenylnicotinamide derivatives as antagonists of TRPV1"
Westaway.MS, et al.
Bioorganic & Medicinal Chemistry, 18(20), 5609-5613 (2008)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 631175-25G | 04061832977911 |
| 631175-5G | 04061832977928 |