634859
3-Methoxy-2-naphthol
97%
Synonym(s):
2-Hydroxy-3-methoxynaphthalene
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About This Item
Linear Formula:
CH3OC10H6OH
CAS Number:
Molecular Weight:
174.20
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Assay
97%
form
solid
mp
107-111 °C (lit.)
SMILES string
COc1cc2ccccc2cc1O
InChI
1S/C11H10O2/c1-13-11-7-9-5-3-2-4-8(9)6-10(11)12/h2-7,12H,1H3
InChI key
SJTNTIRIRIPZDV-UHFFFAOYSA-N
Application
3-Methoxy-2-naphthol can be used in the synthesis of a naphthoate ester, which can act like dopamine D4 antagonist.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Nick D Pokorzynski et al.
eLife, 8 (2019-04-03)
During infection, pathogens are starved of essential nutrients such as iron and tryptophan by host immune effectors. Without conserved global stress response regulators, how the obligate intracellular bacterium Chlamydia trachomatis arrives at a physiologically similar 'persistent' state in response to
Design and synthesis of 2-naphthoate esters as selective dopamine D4 antagonists.
I Boyfield et al.
Journal of medicinal chemistry, 39(10), 1946-1948 (1996-05-10)
Nenad Manevski et al.
Drug metabolism and disposition: the biological fate of chemicals, 43(1), 126-139 (2014-10-24)
Although skin is the largest organ of the human body, cutaneous drug metabolism is often overlooked, and existing experimental models are insufficiently validated. This proof-of-concept study investigated phase II biotransformation of 11 test substrates in fresh full-thickness human skin explants
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