64275
Methanesulfonamide
≥97.0% (CHN)
Synonym(s):
Mesylamide, Methanesulfonic amide, Methanesulphonamide
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About This Item
Linear Formula:
CH3SO2NH2
CAS Number:
Molecular Weight:
95.12
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
221-553-6
Beilstein/REAXYS Number:
1740835
MDL number:
Assay:
≥97.0% (CHN)
Form:
solid
Quality Level
assay
≥97.0% (CHN)
form
solid
mp
85-89 °C (lit.)
SMILES string
CS(N)(=O)=O
InChI
1S/CH5NO2S/c1-5(2,3)4/h1H3,(H2,2,3,4)
InChI key
HNQIVZYLYMDVSB-UHFFFAOYSA-N
Application
- Methanesulfonamide is used in the synthesis of important organic reagents such as N-(2-methylthio-1-p-toluenesufonyl)methanesulfonamide and tert-butyl ((2-(trimethylsilyl)ethyl)sulfonyl)carbamate.
- It can be used as a source of nitrogen in the conversion of carboxylic acids to corresponding nitriles.
- It is widely used as a reagent in the synthesis of medicinally important compounds such as derivatives of indole-N-acetamide, methanesulfonamide pyrimidine-substituted 3,5-dihydroxy-6-heptenoates and repertaxin.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Development and preliminary optimization of indole-N-acetamide inhibitors of hepatitis C virus NS5B polymerase.
Harper S, et al.
Journal of Medicinal Chemistry, 48(5), 1314-1317 (2005)
2-Arylpropionic CXC chemokine receptor 1 (CXCR1) ligands as novel noncompetitive CXCL8 inhibitors.
Allegretti M, et al.
Journal of Medicinal Chemistry, 48(13), 4312-4331 (2005)
Synthesis and biological activity of methanesulfonamide pyrimidine-and N-methanesulfonyl pyrrole-substituted 3, 5-dihydroxy-6-heptenoates, a novel series of HMG-CoA reductase inhibitors.
Watanabe M, et al.
Bioorganic & Medicinal Chemistry, 5(2), 437-444 (1997)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 252840-1G | 04061825977683 |
| 64275-50G | 04061832729565 |
| 64275-10G | 04061832729558 |