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Merck
CN

64940

N-Methoxycarbonylmaleimide

≥97.0% (N)

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About This Item

Empirical Formula (Hill Notation):
C6H5NO4
CAS Number:
Molecular Weight:
155.11
EC Number:
259-792-3
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
1450638
MDL number:
Assay:
≥97.0% (N)
Form:
solid
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Quality Level

assay

≥97.0% (N)

form

solid

mp

63-67 °C

storage temp.

2-8°C

SMILES string

COC(=O)N1C(=O)C=CC1=O

InChI

1S/C6H5NO4/c1-11-6(10)7-4(8)2-3-5(7)9/h2-3H,1H3

InChI key

LLAZQXZGAVBLRX-UHFFFAOYSA-N

Other Notes

For the introduction of the maleimide group in peptides, amino acids and amines


pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Preparation and some properties of maleimido acids and maleoyl derivatives of peptides.
O Keller et al.
Helvetica chimica acta, 58(2), 531-541 (1975-03-12)
Susanne Kirchhof et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 96, 217-225 (2015-08-09)
Eight-armed PEG was functionalized with furyl and maleimide groups (8armPEG20k-Fur and 8armPEG20k-Mal); degradable hydrogels were obtained by cross-linking via Diels-Alder chemistry. To increase the stability to degradation, the macromonomers were modified by introducing a hydrophobic 6-aminohexanoic acid spacer between PEG