653322
1-(2,3,4-Trimethoxybenzyl)piperazine dihydrochloride
97%
Synonym(s):
Trimetazidine dihydrochloride
Sign In to View Organizational & Contract Pricing.
Select a Size
About This Item
Empirical Formula (Hill Notation):
C14H22N2O3 · 2HCl
CAS Number:
Molecular Weight:
339.26
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
236-117-0
MDL number:
Assay:
97%
Form:
solid
InChI key
VYFLPFGUVGMBEP-UHFFFAOYSA-N
InChI
1S/C14H22N2O3.2ClH/c1-17-12-5-4-11(13(18-2)14(12)19-3)10-16-8-6-15-7-9-16;;/h4-5,15H,6-10H2,1-3H3;2*1H
SMILES string
Cl[H].Cl[H].COc1ccc(CN2CCNCC2)c(OC)c1OC
assay
97%
form
solid
mp
231-235 °C (lit.)
Quality Level
Related Categories
Application
1-(2,3,4-Trimethoxybenzyl)piperazine dihydrochloride or trimetazidine dihydrochloride can be used as a building block to synthesize:
- Phenylpropyl trimetazidine derivatives with potent cerebral vasodilator activity.
- Benzoylguanidine-trimetazidine derivatives for myocardial ischemic-reperfusion activity studies.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
监管及禁止进口产品
This item has
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Benzylpiperazine Derivatives. I. Syntheses and Biological Activities of 1 (2, 3, 4-Trimethoxybenzyl) piperazine Derivatives
OHTAKA H, et al.
Chemical & Pharmaceutical Bulletin, 35(7), 2774-2781 (1987)
Design, synthesis and biological evaluation of novel substituted benzoylguanidine derivatives as potent Na+/H+ exchanger inhibitors
Xu W-T, et al.
Bioorganic & Medicinal Chemistry Letters, 19(12), 3283-3287 (2009)
Le Tran Phuc Khoa et al.
Cell stem cell, 27(3), 441-458 (2020-07-02)
Self-renewing embryonic stem cells (ESCs) respond to environmental cues by exiting pluripotency or entering a quiescent state. The molecular basis underlying this fate choice remains unclear. Here, we show that histone acetyltransferase MOF plays a critical role in this process
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service