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Merck
CN

655872

N-Boc-piperidine

98%

Synonym(s):

1-Boc-piperidine, N-(tert-Butoxycarbonyl)piperidine, N-Boc-tetrahydropyridine

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About This Item

Empirical Formula (Hill Notation):
C10H19NO2
CAS Number:
Molecular Weight:
185.26
UNSPSC Code:
12352100
PubChem Substance ID:
MDL number:
Assay:
98%
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InChI

1S/C10H19NO2/c1-10(2,3)13-9(12)11-7-5-4-6-8-11/h4-8H2,1-3H3

SMILES string

CC(C)(C)OC(=O)N1CCCCC1

InChI key

RQCNHUCCQJMSRG-UHFFFAOYSA-N

assay

98%

refractive index

n20/D 1.454 (lit.)

density

0.964 g/mL at 25 °C (lit.)

Application

Reactant for synthesis of:
  • Piperazine derivatives for orally active acetyl-CoA carboxylase 1/2 non-selective inhibitors
  • 2-Aryl and 2-vinyl piperidines
  • Allosteric IGF-1R inhibitors

Reactant for:
  • Allylation and conjugate addition reactions
  • Asymmetric deprotonation
  • Enantioselective inter- and intramolecular aldol reactions
Substrate used in a two-step α-arylation procedure.

pictograms

Skull and crossbonesEnvironment

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

186.8 °F - closed cup

flash_point_c

86 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

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Tetrahedron Letters, 47, 455-455 (2006)

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