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Merck
CN

659630

Polylactide-block-poly(ethylene glycol)-block-polylactide

PLA average Mn 1,500, PEG average Mn 900

Synonym(s):

Nanopatterning, block-copolymers, PLA-PEG-PLA

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About This Item

Linear Formula:
HO(CHCH3COO)x(CH2CH2O)y(COCHCH3O)zH
UNSPSC Code:
12162002
NACRES:
NA.23
MDL number:
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Product Name

Polylactide-block-poly(ethylene glycol)-block-polylactide, PLA average Mn 1,500, PEG average Mn 900

form

solid

mol wt

PEG average Mn 900
PLA average Mn 1,500
average Mn (1,500-900-1,500)

degradation timeframe

<12 months

transition temp

Tm 278.5 °C
Tg 7-9 °C

PDI

<1.2

Quality Level

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Application

The PLA average Mn value of 3,000 is a combined total between the two PLA blocks.

Features and Benefits

Biodegradable polymer. Applications include drug encapsulation and drug delivery.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Articles

Humankind has utilized protein materials throughout its existence, starting with the use of materials such as wool and silk for warmth and protection from the elements and continuing with the use of recombinant DNA techniques to synthesize proteins with unique and useful properties.

AliAliphatic polyesters, including polylactide and polyglycolide, are biodegradable polymers widely used in medical applications.

Interest in utilizing biodegradable polymers for biomedical applications has grown since the 1960s.

Immunosuppressive tumor-associated myeloid cells (TAMC) are responsible for glioblastoma (GBM) resistance to immunotherapies and existing standard of care treatments. This mini-review highlights recent progress in implementing nanotechnology in advancing TAMC-targeted therapies for GBM.

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