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Merck
CN

661422

Sigma-Aldrich

D-Glucose-1,2-13C2

endotoxin tested, 99 atom % 13C

Synonym(s):

Labeled Glucose, Dextrose-1,2-13C2

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About This Item

Empirical Formula (Hill Notation):
13C2C4H12O6
CAS Number:
138079-87-5
Molecular Weight:
182.14
MDL number:
MFCD00144080
UNSPSC Code:
12352001
PubChem Substance ID:
329760194

Key Documents

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isotopic purity

99 atom % 13C

form

solid

optical activity

[α]25/D +52.0°, c = 2 in H2O (trace NH4OH)

mp

150-152 °C (lit.)

suitability

endotoxin tested

mass shift

M+2

SMILES string

OC[C@@H](O)[C@@H](O)[C@H](O)[13C@@H](O)[13CH]=O

InChI

1S/C6H12O6/c7-1-3(9)5(11)6(12)4(10)2-8/h1,3-6,8-12H,2H2/t3-,4+,5+,6+/m0/s1/i1+1,3+1

InChI key

GZCGUPFRVQAUEE-SZEFTZBMSA-N

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General description

ᴅ-Glucose-1,2-13C2 endotoxin tested, 99 atom % 13C is a high-purity isotope product with a unique chemical profile that belongs to the class of isotopes. Produced by Sigma-Aldrich, we are committed to providing quality isotope products and a reliable supply chain. Available in industrial and pre-pack quantities.

Application

- metabolic flux analysis in cellular systems
- NMR studies of glucose metabolism pathways
- Diabetes and metabolic disorder research
- glucose metabolism studies in Diabetes research

Features and Benefits

Features
- High-quality solvent for analytical applications
- Improves accuracy in structural analyses
- Non-toxic and environmentally friendly
- Supports a variety of research applications

Benefits
- Ensures high-quality results in analytical experiments
- Increases reliability of obtained data
- Facilitates understanding of complex interactions
- Supports effective therapy development

Packaging

This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
CX1947

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Keith R Laderoute et al.
The Journal of biological chemistry, 289(33), 22850-22864 (2014-07-06)
Rapid tumor growth can establish metabolically stressed microenvironments that activate 5'-AMP-activated protein kinase (AMPK), a ubiquitous regulator of ATP homeostasis. Previously, we investigated the importance of AMPK for the growth of experimental tumors prepared from HRAS-transformed mouse embryo fibroblasts and
Teresa W-M Fan et al.
Bio-protocol, 6(3) (2016-05-10)
An important component of this methodology is to assess the role of the tumor microenvironment on tumor growth and survival. To tackle this problem, we have adapted the original approach of Warburg 1, by combining thin tissue slices with Stable
Andrew N Lane et al.
Bio-protocol, 5(22) (2015-12-23)
Mice are widely used for human tumor xenograft studies of cancer development and drug efficacy and toxicity. Stable isotope tracing coupled with metabolomic analysis is an emerging approach for assaying metabolic network activity. In mouse models there are several routes

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