Skip to Content
Merck
CN

Key Documents

View All Documentation

676632

5-(Di-tert-butylphosphino)-1′, 3′, 5′-triphenyl-1′H-[1,4′]bipyrazole

97%, solid

Synonym(s):

BippyPhos

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):
C32H35N4P
CAS Number:
894086-00-1
Molecular Weight:
506.62
UNSPSC Code:
12352005
PubChem Substance ID:
24884860
NACRES:
NA.22
MDL number:
MFCD09038440
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

5-(Di-tert-butylphosphino)-1′, 3′, 5′-triphenyl-1′H-[1,4′]bipyrazole, 97%

Quality Level

100

assay

97%

form

solid

reaction suitability

reaction type: Cross Couplings, reagent type: ligand
reaction type: Amidations, reagent type: ligand
reaction type: Buchwald-Hartwig Cross Coupling Reaction, reagent type: ligand
reaction type: Coupling Reactions

mp

169-173 °C

functional group

phosphine

SMILES string

CC(C)(C)P(c1ccnn1-c2c(nn(-c3ccccc3)c2-c4ccccc4)-c5ccccc5)C(C)(C)C

InChI

1S/C32H35N4P/c1-31(2,3)37(32(4,5)6)27-22-23-33-36(27)30-28(24-16-10-7-11-17-24)34-35(26-20-14-9-15-21-26)29(30)25-18-12-8-13-19-25/h7-23H,1-6H3

InChI key

PTXJGGGNGMPMBG-UHFFFAOYSA-N

Application

Non-proprietary ligand for palladium-catalyzed amination of aryl halides including aryl chlorides. Works best when the palladium source is Pd2(dba)3 (328774).

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
MKCW6921
MKCM8173
MKCL9159
MKCL1725
MKCJ0125

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Related Content

Phosphine Ligand Application Guide

Phosphine Ligand Application Guide

Achim Porzelle et al.
Organic letters, 11(1), 233-236 (2008-11-28)
The bis-pyrazole phosphine ligand BippyPhos is effective for the palladium-catalyzed cross-coupling of hydroxylamines with aryl bromides, chlorides, and iodides. Reactions proceed smoothly at 80 degrees C in toluene in the presence of Cs(2)CO(3) to give synthetically versatile N-arylhydroxylamine products in
Brian J Kotecki et al.
Organic letters, 11(4), 947-950 (2009-01-31)
A general and practical method for the preparation of unsymmetrically substituted ureas has been developed utilizing palladium-catalyzed amidation. Both aryl bromides and chlorides, as well as heteroaryl chlorides, have been coupled to aryl, benzyl, and aliphatic ureas by using a
Saravanan Gowrisankar et al.
Journal of the American Chemical Society, 132(33), 11592-11598 (2010-08-03)
An efficient procedure for palladium-catalyzed coupling reactions of (hetero)aryl bromides and chlorides with primary aliphatic alcohols has been developed. Key to the success is the synthesis and exploitation of the novel bulky di-1-adamantyl-substituted bipyrazolylphosphine ligand L6. Reaction of aryl halides
View All Related Papers

Global Trade Item Number

SKUGTIN
676632-250MG04061833549704
676632-1G04061826733493