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Merck
CN

683787

2-(Trifluoromethoxy)phenylboronic acid

≥95%

Synonym(s):

2-(Trifluoromethoxy)benzeneboronic acid

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About This Item

Linear Formula:
F3CO(C6H4)B(OH)2
CAS Number:
Molecular Weight:
205.93
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352103
MDL number:
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InChI

1S/C7H6BF3O3/c9-7(10,11)14-6-4-2-1-3-5(6)8(12)13/h1-4,12-13H

SMILES string

OB(O)c1ccccc1OC(F)(F)F

InChI key

AIJCNTOYZPKURP-UHFFFAOYSA-N

assay

≥95%

form

powder or crystals

functional group

fluoro

General description

May contain varying amounts of anhydride.

Application

Reactant for:
  • Preparation of imidazo[1,5-a]pyrido[3,2-e]pyrazines and imidazo[1,5-a]quinoxalines as orally active phosphodiesterase 10A inhibitors
  • Suzuki-Miyaura cross-coupling reactions
  • Preparation of 3-(5-arylbenzimidazol-2-yl)-1-oxa-2-azaspiro[4.5]decenes as transient receptor potential melastatin 8 antagonists
  • Preparation of biaryl pyrazole carboxamides as sodium channel blockers for treatment of neuropathic pain
  • Preparation of biaryl oxazoles, imidazoles and thiazoles via condensations as sodium channel blockers and CYP inhibitors for treatment of neuropathic pain

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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