706574
N-Boc-cis-4-hydroxy-D-proline
97%
Synonym(s):
(2R,4R)-N-Boc-4-hydroxy-2-pyrrolidinecarboxylic acid
Sign In to View Organizational & Contract Pricing.
Select a Size
About This Item
Empirical Formula (Hill Notation):
C10H17NO5
CAS Number:
Molecular Weight:
231.25
UNSPSC Code:
12352005
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.22
MDL number:
SMILES string
CC(C)(C)OC(=O)N1C[C@H](O)C[C@@H]1C(O)=O
InChI
1S/C10H17NO5/c1-10(2,3)16-9(15)11-5-6(12)4-7(11)8(13)14/h6-7,12H,4-5H2,1-3H3,(H,13,14)/t6-,7-/m1/s1
InChI key
BENKAPCDIOILGV-RNFRBKRXSA-N
assay
97%
form
solid
optical activity
[α]22/D +50.0°, c = 1 in methanol
mp
146-151 °C
application(s)
peptide synthesis
functional group
carboxylic acid, hydroxyl
storage temp.
2-8°C
Application
N-Boc-cis-4-hydroxy-D-proline can be used:
- As a starting material in the synthesis of DNA mimicking pyrrolidine peptide nucleic acid (PNA) analog.
- In the synthesis of biologically important macrocyclic dilactones.
- As an intermediate in the synthesis of histamine H3 receptor antagonists.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Eye Irrit. 2
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
新产品
This item has
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Synthesis of macrocyclic dilactones by cyclization of sulfonium salts
Nakamura T, et al.
The Journal of Organic Chemistry, 57(14), 3783-3789 (1992)
Novel substituted pyrrolidines are high affinity histamine H3 receptor antagonists
Stocking EM, et al.
Bioorganic & Medicinal Chemistry Letters, 20(9), 2755-2760 (2010)
Pyrrolidine PNA: A novel conformationally restricted PNA analogue
Puschl A, et al.
Organic Letters, 2(26), 4161-4163 (2000)
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service