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70800

5-Amino-1-naphthalenesulfonic acid

Name: 5-Amino-1-naphthalenesulfonic acid
Brand: ALDRICH

technical, ≥60.0% (T)

Synonym(s):

1-Naphthylamine-5-sulfonic acid, Laurent’s acid

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About This Item

Empirical Formula (Hill Notation):

C₁₀H₉NO₃S

CAS Number:

84-89-9

Molecular Weight:

223.25

UNSPSC Code:

12352100

NACRES:

NA.22

PubChem Substance ID:

57652262

EC Number:

201-571-0

Beilstein/REAXYS Number:

2214149

MDL number:

MFCD00014315

Form:

powder

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Properties

grade

technical

form

powder

concentration

≥60.0% (T)

SMILES string

Nc1cccc2c(cccc12)S(O)(=O)=O

InChI

1S/C10H9NO3S/c11-9-5-1-4-8-7(9)3-2-6-10(8)15(12,13)14/h1-6H,11H2,(H,12,13,14)

InChI key

DQNAQOYOSRJXFZ-UHFFFAOYSA-N

Description

pictograms

GHS05,GHS07

signalword

Danger

hcodes

H312 + H332,H314

pcodes

P260 - P271 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 4 Dermal - Skin Corr. 1B

Storage Class

8B - Non-combustible corrosive hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Regulatory Information

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Controlling {beta}-amyloid oligomerization by the use of naphthalene sulfonates: trapping low molecular weight oligomeric species.

Astria D Ferrão-Gonzales et al.

The Journal of biological chemistry, 280(41), 34747-34754 (2005-07-26)

Aggregation of proteins and peptides has been shown to be responsible for several diseases known as amyloidoses, which include Alzheimer disease (AD), prion diseases, among several others. AD is a neurodegenerative disorder caused primarily by the aggregation of beta-amyloid peptide

Synthesis and characterization of fluorescent dinucleotide substrate for the DNA-dependent RNA polymerase from Escherichia coli.

S C Tyagi et al.

The Journal of biological chemistry, 262(22), 10684-10688 (1987-08-05)

New fluorescent derivatives of dinucleoside monophosphates, (5'-AmNS)UpA/ApU/GpU/CpA, with a fluorophore, 1-aminonaphthalene-5-sulfonic acid (AmNS), attached to the first nucleotide of the dinucleoside monophosphates via a 5'-secondary amine linkage were synthesized in good yield. The chemical structure of (5'-AmNS)ApU was proved by

Catalytic Production of Oxo-fatty Acids by Lipoxygenases Is Mediated by the Radical-Radical Dismutation between Fatty Acid Alkoxyl Radicals and Fatty Acid Peroxyl Radicals in Fatty Acid Assembly.

Yuta Takigawa et al.

Chemical & pharmaceutical bulletin, 68(3), 258-264 (2020-03-03)

Oxo-octadecadienoic acids (OxoODEs) act as peroxisome proliferator-activated receptor (PPAR) agonists biologically, and are known to be produced in the lipoxygenase/linoleate system. OxoODEs seem to originate from the linoleate alkoxyl radicals that are generated from (E/Z)-hydroperoxy octadecadienoic acids ((E/Z)-HpODEs) by a

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Global Trade Item Number

SKU	GTIN
901221-1G	04061835168057
70800-100G	04061832843056