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Merck
CN

70800

Sigma-Aldrich

5-Amino-1-naphthalenesulfonic acid

technical, ≥60.0% (T)

Synonym(s):

1-Naphthylamine-5-sulfonic acid, Laurent’s acid

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About This Item

Empirical Formula (Hill Notation):
C10H9NO3S
CAS Number:
Molecular Weight:
223.25
Beilstein:
2214149
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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grade

technical

form

powder

concentration

≥60.0% (T)

SMILES string

Nc1cccc2c(cccc12)S(O)(=O)=O

InChI

1S/C10H9NO3S/c11-9-5-1-4-8-7(9)3-2-6-10(8)15(12,13)14/h1-6H,11H2,(H,12,13,14)

InChI key

DQNAQOYOSRJXFZ-UHFFFAOYSA-N

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Pictograms

CorrosionExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 4 Dermal - Skin Corr. 1B

Storage Class Code

8B - Non-combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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G Dhar et al.
The Journal of biological chemistry, 274(21), 14568-14572 (1999-05-18)
Intramolecular aromatic interactions in aqueous solution often lead to stacked conformation for model organic molecules. This designing principle was used to develop stacked and folded uridine nucleotide analogs that showed highly quenched fluoroscence in aqueous solution by attaching the fluorophore
R R Kardost et al.
Molecular immunology, 19(1), 159-170 (1982-01-01)
A fluorescence immune assay designed to measure anti-nucleotide antibody activity is described based on the synthesis of a fluorescent nucleotide probe possessing a low fluorescence quantum yield when free in aqueous solution (neutral pH). The fluorophore, AmNS (1-naphthylamine-5-sulfonic acid), was
P S Reddy et al.
Molecular microbiology, 15(2), 255-265 (1995-01-01)
On amino acid starvation, Escherichia coli cells exhibit an adaptive facility termed the stringent response. This is characterized by the production of high levels of a regulatory nucleotide, ppGpp, and concomitant curtailment in rRNA synthesis. Various studies reported earlier indicated
Fluorescent nucleotide triphosphate substrates for snake venom phosphodiesterase.
S E Pollack et al.
Analytical biochemistry, 127(1), 81-88 (1982-11-15)
Astria D Ferrão-Gonzales et al.
The Journal of biological chemistry, 280(41), 34747-34754 (2005-07-26)
Aggregation of proteins and peptides has been shown to be responsible for several diseases known as amyloidoses, which include Alzheimer disease (AD), prion diseases, among several others. AD is a neurodegenerative disorder caused primarily by the aggregation of beta-amyloid peptide

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