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Merck
CN

724467

Poly(N-isopropylacrylamide-co-methacrylic acid)

methacrylic acid 5 mol %, average Mn 50,000

Synonym(s):

Poly(NIPAM-co-MAA), Polyacrylamide, functionalized polyNIPAM, functionalized polyacrylamide, polyNIPAM

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About This Item

Linear Formula:
(C6H11NO)m (C4H6O2)n
CAS Number:
UNSPSC Code:
12162002
NACRES:
NA.23
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Product Name

Poly(N-isopropylacrylamide-co-methacrylic acid), methacrylic acid 5 mol %, average Mn 50,000

InChI

1S/C6H11NO.C4H6O2/c1-4-6(8)7-5(2)3;1-3(2)4(5)6/h4-5H,1H2,2-3H3,(H,7,8);1H2,2H3,(H,5,6)

InChI key

BGJOTKHBFYMJST-UHFFFAOYSA-N

form

powder

mol wt

average Mn 50,000

composition

methacrylic acid, 5 mol %

mp

>300 °C

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Application

Intelligent Swelling/Collapsing copolymer that can be used as a temperature- and pH-sensitive materials.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Preparation and characterization of thermal- and pH-sensitive nanospheres.
X Y Wu et al.
Pharmaceutical research, 10(10), 1544-1547 (1993-10-01)
Yashpal Sharma et al.
International journal of biological macromolecules, 51(4), 627-631 (2012-06-23)
Electrospinning is a versatile method to fabricate nanofibers of a range of polymeric and composite materials suitable as scaffolds for tissue engineering applications. In this study, we report the fabrication and characterization of polyaniline-carbon nanotube/poly(N-isopropyl acrylamide-co-methacrylic acid) (PANI-CNT/PNIPAm-co-MAA) composite nanofibers
Synthesis of novel metal sulfide-polymer composite microspheres exhibiting patterned surface structures.
Chaoliang Bai et al.
Langmuir : the ACS journal of surfaces and colloids, 20(1), 263-265 (2005-03-05)
Eva Díez-Peña et al.
AAPS PharmSciTech, 5(2), e33-e33 (2005-03-12)
A series of poly[(N-isopropylacrylamide)-co-(methacrylic acid)] (P[(N-iPAAm)-co-(MAA)]) hydrogels was investigated to determine the composition that exhibits a better pH-modulated release of diltiazem hydrochloride (DIL.HCl). For this purpose hydrogel slabs were loaded with DIL.HCl by the immersion method, and its release under
Ana M Díez-Pascual et al.
Journal of colloid and interface science, 347(1), 79-89 (2010-04-14)
The confinement of polyelectrolyte multilayers of poly-L-lysine (PLL)/poly-L-glutamic acid (PGA) and chitosan (CHIT)/dextran sulfate (DEX) onto soft and porous thermoresponsive poly(N-isopropylacrylamide-co-methacrylic acid) (P(NiPAM-co-MAA)) microgel was studied by dynamic light scattering (DLS) and electrophoretic measurements. DLS demonstrates an "odd-even" effect in

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Biomaterials science integrates smart materials into biological research, requiring a deep understanding of biological systems.

Microparticles in drug delivery: Study on controlling chitosan microparticle size and distribution, exploring encapsulation of BSA and TPP cross-linker.

Poly(N-isopropylacrylamide), or PNIPAM, is a stimuli-responsive polymer that responds to changes in pH and temperature and has a LCST around 32 C.

Professor Mitsuhiro Ebara provides insights on several types of smart nanofiber mesh systems that have been explored for different drug delivery purposes.

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