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Merck
CN

724475

Poly(N-isopropylacrylamide-co-methacrylic acid-co-octadecyl acrylate)

5 mol % in methacrylic acid, 1 mol % in octadecyl acrylate, Mn 30,000-60,000

Synonym(s):

Poly(NIPAM-co-MAA-co-ODA), Polyacrylamide, functionalized polyNIPAM, functionalized polyacrylamide, polyNIPAM

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About This Item

Linear Formula:
(C6H11NO)m (C4H6O2)n (C21H40O2)p
NACRES:
NA.23
UNSPSC Code:
12162002
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form

powder

mol wt

Mn 30,000-60,000

concentration

1 mol % in octadecyl acrylate, 5 mol % in methacrylic acid

mp

>300 °C

General description

Intelligent Swelling/Collapsing copolymer that can be used as a temperature- and pH-sensitive material.

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Quijada-Garrido; I.; Prior-Cabanillas; A.; Garrido; L.; Barrales-Rienda; J. M.
Macromolecules, 38, 7434-7434 (2005)
Salgado-Rodriguez; R.; Licea-Claverie; A.; Arndt; K. F.
Eur. Polymer J., 40, 1931-1931 (2004)

Articles

Poly(N-isopropylacrylamide), or PNIPAM, is a stimuli-responsive polymer that responds to changes in pH and temperature and has a LCST around 32 C.

By altering the physicochemical properties, smart or intelligent drug delivery systems can be designed to deliver therapeutic molecules on-demand. Learn more about the application of stimuli-responsive materials in drug delivery.

Tissue engineering has become a key therapeutic tool in the treatment of damaged or diseased organs and tissues, such as blood vessels and urinary bladders.

通过调整的理化特性,药物递送系统可根据需要设计为可递送治疗分子的智能系统。了解有关刺激响应材料药物递送应用的更多信息。

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