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Merck
CN

724858

Poly(N-isopropylacrylamide-co-methacrylic acid)

methacrylic acid 10 mol %, Mn 60,000

Synonym(s):

Poly(NIPAM-co-MAA), Polyacrylamide, functionalized polyNIPAM, functionalized polyacrylamide, polyNIPAM

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About This Item

Linear Formula:
(C6H11NO)m (C4H6O2)n
CAS Number:
151954-97-1
MDL number:
MFCD00284282
UNSPSC Code:
12162002
NACRES:
NA.23

Key Documents

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Product Name

Poly(N-isopropylacrylamide-co-methacrylic acid), methacrylic acid 10 mol %, Mn 60,000

form

solid

SMILES string

N(C(C)C)C(=O)C=C.OC(=O)C(=C)C

InChI

1S/C6H11NO.C4H6O2/c1-4-6(8)7-5(2)3;1-3(2)4(5)6/h4-5H,1H2,2-3H3,(H,7,8);1H2,2H3,(H,5,6)

InChI key

BGJOTKHBFYMJST-UHFFFAOYSA-N

mol wt

Mn 60,000

composition

methacrylic acid, 10 mol %

mp

>300 °C

Mw/Mn

≤2.5

Quality Level

100

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Related Categories

Application

PNIPAM-based Smart Surfaces for Cell Sheet Tissue Engineering
Intelligent Swelling/Collapsing copolymer that can be used as a temperature- and pH-sensitive materials.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
MKCF2244
MKBN4229V
MKBF2188

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Weitai Wu et al.
Biosensors & bioelectronics, 25(12), 2603-2610 (2010-05-18)
A new class of optical glucose nanobiosensors with high sensitivity and selectivity at physiological pH is described. To construct these glucose nanobiosensors, the fluorescent CdS quantum dots (QDs), serving as the optical code, were incorporated into the glucose-sensitive poly(N-isopropylacrylamide-acrylamide-2-acrylamidomethyl-5-fluorophenylboronic acid)
Sabrina Schmidt et al.
Langmuir : the ACS journal of surfaces and colloids, 27(16), 9801-9806 (2011-07-09)
Charged poly(N-isopropylacrylamide-co-methacrylic acid) [P(NiPAM-co-MAA)] microgels can stabilize thermo- and pH-sensitive emulsions. By placing charged units at different locations in the microgels and comparing the emulsion properties, we demonstrate that their behaviors as emulsion stabilizers are very different from molecular surfactants
J Moselhy et al.
Journal of biomaterials science. Polymer edition, 11(2), 123-147 (2000-03-16)
The pH- and temperature-responsive poly(N-isopropylacrylamide-co-methacrylic acid) (PNIPAm/MAA) nanoparticles are of potential application in targeted drug delivery. Their responsive properties in the presence of human serum albumin were investigated using dynamic light scattering (DLS), protein assay, and electron spin resonance (ESR)
Pierre Simard et al.
International journal of pharmaceutics, 381(2), 86-96 (2009-05-19)
A promising avenue in cancer therapy using liposomal formulations is the combination of site-specific delivery with triggered drug release. The use of trigger mechanisms in liposomes could be relevant for drugs susceptible to lysosomal hydrolytic/enzymatic degradation. Here, we propose a
Eunice Costa et al.
Langmuir : the ACS journal of surfaces and colloids, 28(26), 10082-10090 (2012-06-09)
The layer-by-layer (LbL) assembly of polyelectrolyte pairs on temperature and pH-sensitive cross-linked poly(N-isopropylacrylamide)-co-(methacrylic acid), poly(NIPAAm-co-MAA), microgels enabled a fine-tuning of the gel swelling and responsive behavior according to the mobility of the assembled polyelectrolyte (PE) pair and the composition of
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