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Merck
CN

73200

O-(4-Nitrobenzyl)hydroxylamine hydrochloride

≥98.5% (AT)

Synonym(s):

4-Nitrobenzyloxyamine hydrochloride

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About This Item

Linear Formula:
O2NC6H4CH2ONH2 · HCl
CAS Number:
Molecular Weight:
204.61
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
218-228-6
Beilstein/REAXYS Number:
3709565
MDL number:
Assay:
≥98.5% (AT)
Form:
crystals
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Product Name

O-(4-Nitrobenzyl)hydroxylamine hydrochloride, ≥98.5% (AT)

Quality Level

InChI key

LKCAFSOYOMFQSL-UHFFFAOYSA-N

InChI

1S/C7H8N2O3.ClH/c8-12-5-6-1-3-7(4-2-6)9(10)11;/h1-4H,5,8H2;1H

SMILES string

Cl.NOCc1ccc(cc1)[N+]([O-])=O

assay

≥98.5% (AT)

form

crystals

mp

215 °C (dec.) (lit.)

functional group

nitro

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Other Notes

Reagent for the preparation of N-(4-nitrobenzyloxy)-amino acids as substrates for an unambiguous N-hydroxypeptide synthesis

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Kenneth P Roberts et al.
Chemical research in toxicology, 19(2), 300-309 (2006-02-21)
A new method has been developed to accurately measure apurinic and apyrimidinic (AP) DNA damage sites, which are lesions in DNA formed by loss of a nucleobase from oxidative stress or carcinogen adducts. If AP sites are left unrepaired (or
M Pauly et al.
Planta, 212(5-6), 842-850 (2001-05-12)
Xyloglucans were isolated by sequential extraction of the cell walls of pea (Pisum sativum L. cv. Alaska) with a xyloglucan-specific endoglucanase and KOH. The xyloglucan content and xyloglucan-oligosaccharide composition were determined for fractions obtained from the elongating and non-elongating segments
T D Traylor et al.
Journal of chromatography, 272(1), 9-20 (1983-01-14)
A new quantitative procedure for the high-performance liquid chromatographic (HPLC) resolution of human brain gangliosides employing reversed-phase chromatography is described. To provide a derivative which can be determined by UV absorption techniques, p-nitrobenzyloxyamine was coupled to the gangliosides. Derivatization involves
Joo Hyun Lim et al.
Frontiers in microbiology, 9, 2333-2333 (2018-10-16)
2-Deoxy-scyllo-inosose (DOI) has been a valuable starting natural product for the manufacture of pharmaceuticals or chemical engineering resources such as pyranose catechol. DOI synthase, which uses glucose-6-phosphate (Glc6P) as a substrate for DOI biosynthesis, is indispensably involved in the initial
B X Chen et al.
Mutation research, 273(3), 253-261 (1992-05-01)
The abasic site is one of the most frequent changes occurring in DNA and has been shown to be lethal and mutagenic. An abasic site in DNA can be tagged by reaction with O-4-nitrobenzylhydroxylamine (NBHA), resulting in the formation of

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