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740683

1,8-Dihydroxynaphthalene

95%

Synonym(s):

1,8-Naphthalenediol

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About This Item

Empirical Formula (Hill Notation):
C10H8O2
CAS Number:
569-42-6
Molecular Weight:
160.17
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
329765431
MDL number:
MFCD00042701
Beilstein/REAXYS Number:
2044947
Assay:
95%
Form:
solid
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Quality Level

100

assay

95%

form

solid

mp

137-143 °C

storage temp.

2-8°C

SMILES string

Oc1cccc2cccc(O)c12

InChI

1S/C10H8O2/c11-8-5-1-3-7-4-2-6-9(12)10(7)8/h1-6,11-12H

InChI key

OENHRRVNRZBNNS-UHFFFAOYSA-N

Application

1,8-Dihydroxynaphthalene (DHN) can be used as:
  • An intermediate in the preparation of benzo analogs of spiromamakone A.
  • A starting material to synthesize naphthopyran derivatives.
  • An intermediate in the total synthesis of palmarumycin CP17 analogs.

pictograms

Corrosion
GHS05

signalword

Danger

hcodes

H318

Hazard Classifications

Eye Dam. 1

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
MKDB2737
MKCW3985
MKCT1663
MKCS2303
MKCQ6385

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R Romero-Martinez et al.
Infection and immunity, 68(6), 3696-3703 (2000-05-19)
Sporothrix schenckii is a human pathogen that causes sporotrichosis, an important cutaneous mycosis with a worldwide distribution. It produces dark-brown conidia, which infect the host. We found that S. schenckii synthesizes melanin via the 1,8-dihydroxynaphthalene pentaketide pathway. Melanin biosynthesis in
Bo Wang et al.
BMC genomics, 18(1), 729-729 (2017-09-17)
Ectophytic fungi occupy the waxy plant surface, an extreme environment characterized by prolonged desiccation, nutrient limitation, and exposure to solar radiation. The nature of mechanisms that facilitate adaptation to this environment remains unclear. In this study, we sequenced the complete
N A Yurlova et al.
Studies in mycology, 61, 39-49 (2008-01-01)
Dothideaceous black yeast-like fungi (BYF) are known to synthesise DHN-melanin that is inhibited by the systemic fungicide tricyclazole. The final step of the DHN melanin pathway is the conjoining of 1,8-DHN molecules to form the melanin polymer. There are several
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Global Trade Item Number

SKUGTIN
740683-1G04061832884394